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- W2078240361 abstract "This report is concerned with the origin and elaboration of melanin in the retinal epithelium of Amblystoma punctatum. The animals used in this study developed from a single clutch of unpigmented eggs. The tapetum of such animals is devoid of ovarian pigment and, consequently, the initial formation of melanin can be readily followed. Specifically examined is the possibility of active involvement of melanocytes in the formation of tapetal pigment. Eyes were transplanted from embryos at stage 32+ into the gill region and ventral flank of embryos at stage 28. Data were obtained concerning the initial appearance of melanin and its subsequent elaboration in the tapetum of the grafts correlated with the presence or absence of melanocytes in the immediate vicinity. Melanin first appears in the flank grafts two to three days before melanocytes reach the area. Sequence of melanin elaboration in both types of graft follows more closely that of the donor animals than that of the less advanced hosts. Melanin always appears first in the anterior portion of both grafts and intact eyes, despite the fact that melanocytes are just as closely associated with the posterior pole of the eyes. It is concluded that melanin production is an intrinsic property of the retinal epithelium in Amblystoma." @default.
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- W2078240361 date "1966-12-01" @default.
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- W2078240361 title "Origin and development of retinal melanin inAmblystoma punctatum devoid of ovarian pigment" @default.
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- W2078240361 doi "https://doi.org/10.1002/jez.1401630304" @default.
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