FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078242611> ?p ?o ?g. }

• W2078242611 endingPage "185" @default.
• W2078242611 startingPage "179" @default.
• W2078242611 abstract "Survival after volunteer unrelated donor (VUD) stem cell transplantation (SCT) is influenced by matching for human leucocyte antigens (HLA). We analysed the effects of serological and molecular typing at HLA-A, -B, -C and -DRB1 in 100 patient/VUD pairs from a single transplant centre. Patients received SCT for good risk [chronic myeloid leukaemia in first chronic phase (CML-CP1), n = 55] or poor risk (n = 45) diseases after myeloablative conditioning and T-cell depletion with alemtuzumab. By serological typing, 70 pairs were fully matched, whereas molecular typing revealed 10 pairs with additional mismatches. The day 100 transplant related mortality was 15%. Acute graft versus host disease (GvHD) grades III–IV occurred in 11%, whilst extensive chronic GvHD in 13% of evaluable patients. There was no statistical difference in GvHD rates between patients who received grafts from fully matched or from mismatched donors. In univariate analysis the disease risk group and CMV seronegativity of recipient and donor were the only significant predictors for survival, with 3-year survival probabilities of 71.2% for CML-CP1 and 28% for poor risk diseases. In the poor risk group, HLA mismatches had a negative impact on survival (p = 0.003) and progression free survival (p = 0.009) contrary to CML-CP1 patients, in whom HLA mismatches at molecular or serological level did not have any impact." @default.
• W2078242611 created "2016-06-24" @default.
• W2078242611 creator A5021822775 @default.
• W2078242611 creator A5038348769 @default.
• W2078242611 creator A5039305143 @default.
• W2078242611 creator A5039425378 @default.
• W2078242611 creator A5040507617 @default.
• W2078242611 creator A5041128935 @default.
• W2078242611 creator A5062572365 @default.
• W2078242611 creator A5066230079 @default.
• W2078242611 creator A5074115908 @default.
• W2078242611 creator A5078806215 @default.
• W2078242611 creator A5079491667 @default.
• W2078242611 date "2007-11-01" @default.
• W2078242611 modified "2023-10-16" @default.
• W2078242611 title "Impact of HLA class I and class II DNA high-resolution HLA typing on clinical outcome in adult unrelated stem cell transplantation after in vivo T-cell depletion with alemtuzumab" @default.
• W2078242611 cites W1964016291 @default.
• W2078242611 cites W1965323808 @default.
• W2078242611 cites W1991239009 @default.
• W2078242611 cites W1994780830 @default.
• W2078242611 cites W2002083175 @default.
• W2078242611 cites W2004145859 @default.
• W2078242611 cites W2008629467 @default.
• W2078242611 cites W2029972048 @default.
• W2078242611 cites W2051205528 @default.
• W2078242611 cites W2054998224 @default.
• W2078242611 cites W2062802654 @default.
• W2078242611 cites W2071531342 @default.
• W2078242611 cites W2073236922 @default.
• W2078242611 cites W2074409054 @default.
• W2078242611 cites W2117344753 @default.
• W2078242611 cites W2135240885 @default.
• W2078242611 cites W2149601535 @default.
• W2078242611 cites W2167541030 @default.
• W2078242611 cites W2169978372 @default.
• W2078242611 cites W2170521198 @default.
• W2078242611 cites W2321157084 @default.
• W2078242611 cites W2326052041 @default.
• W2078242611 cites W2332132306 @default.
• W2078242611 cites W2341215846 @default.
• W2078242611 cites W48176394 @default.
• W2078242611 doi "https://doi.org/10.1016/j.trim.2007.05.002" @default.
• W2078242611 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18005865" @default.
• W2078242611 hasPublicationYear "2007" @default.
• W2078242611 type Work @default.
• W2078242611 sameAs 2078242611 @default.
• W2078242611 citedByCount "6" @default.
• W2078242611 countsByYear W20782426112012 @default.
• W2078242611 countsByYear W20782426112015 @default.
• W2078242611 countsByYear W20782426112020 @default.
• W2078242611 crossrefType "journal-article" @default.
• W2078242611 hasAuthorship W2078242611A5021822775 @default.
• W2078242611 hasAuthorship W2078242611A5038348769 @default.
• W2078242611 hasAuthorship W2078242611A5039305143 @default.
• W2078242611 hasAuthorship W2078242611A5039425378 @default.
• W2078242611 hasAuthorship W2078242611A5040507617 @default.
• W2078242611 hasAuthorship W2078242611A5041128935 @default.
• W2078242611 hasAuthorship W2078242611A5062572365 @default.
• W2078242611 hasAuthorship W2078242611A5066230079 @default.
• W2078242611 hasAuthorship W2078242611A5074115908 @default.
• W2078242611 hasAuthorship W2078242611A5078806215 @default.
• W2078242611 hasAuthorship W2078242611A5079491667 @default.
• W2078242611 hasConcept C126322002 @default.
• W2078242611 hasConcept C143998085 @default.
• W2078242611 hasConcept C144301174 @default.
• W2078242611 hasConcept C147483822 @default.
• W2078242611 hasConcept C159654299 @default.
• W2078242611 hasConcept C188280979 @default.
• W2078242611 hasConcept C203014093 @default.
• W2078242611 hasConcept C2777408962 @default.
• W2078242611 hasConcept C2779015954 @default.
• W2078242611 hasConcept C2779972918 @default.
• W2078242611 hasConcept C2911091166 @default.
• W2078242611 hasConcept C38180746 @default.
• W2078242611 hasConcept C45189115 @default.
• W2078242611 hasConcept C71924100 @default.
• W2078242611 hasConceptScore W2078242611C126322002 @default.
• W2078242611 hasConceptScore W2078242611C143998085 @default.
• W2078242611 hasConceptScore W2078242611C144301174 @default.
• W2078242611 hasConceptScore W2078242611C147483822 @default.
• W2078242611 hasConceptScore W2078242611C159654299 @default.
• W2078242611 hasConceptScore W2078242611C188280979 @default.
• W2078242611 hasConceptScore W2078242611C203014093 @default.
• W2078242611 hasConceptScore W2078242611C2777408962 @default.
• W2078242611 hasConceptScore W2078242611C2779015954 @default.
• W2078242611 hasConceptScore W2078242611C2779972918 @default.
• W2078242611 hasConceptScore W2078242611C2911091166 @default.
• W2078242611 hasConceptScore W2078242611C38180746 @default.
• W2078242611 hasConceptScore W2078242611C45189115 @default.
• W2078242611 hasConceptScore W2078242611C71924100 @default.
• W2078242611 hasIssue "2" @default.
• W2078242611 hasLocation W20782426111 @default.
• W2078242611 hasLocation W20782426112 @default.
• W2078242611 hasOpenAccess W2078242611 @default.
• W2078242611 hasPrimaryLocation W20782426111 @default.
• W2078242611 hasRelatedWork W1978645003 @default.
• W2078242611 hasRelatedWork W1994968709 @default.
• W2078242611 hasRelatedWork W2124034872 @default.

• next