Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078242664> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2078242664 endingPage "630" @default.
- W2078242664 startingPage "624" @default.
- W2078242664 abstract "The in vitro hepatic microsomal metabolism of N-(4-chlorobenzyl)-N′-benzoylhydrazine (CBBAH), a model compound representing N-alkyl substituted hydrazides, was studied using hepatic washed rat microsomal preparations fortified with NADPH to identify the possible N-oxidative, N-dealkylated and hydrolytic metabolites. CBBAH and its potential metabolites were prepared, characterized using spectroscopic techniques and then separated using a reversed phase HPLC system with UV detection at 254 nm. CBBAH was chemically converted to the corresponding hydrazone by m-chloroperbenzoic acid (m-CPBA) oxidation. CBBAH was incubated with rat microsomal preparations in the presence of NADPH, extracted into dichloromethane and evaporated finally under nitrogen. The TLC and HPLC results from the metabolic experiments showed that CBBAH produced the corresponding hydrolytic and N-dealkylated metabolites together with the corresponding hydrazone." @default.
- W2078242664 created "2016-06-24" @default.
- W2078242664 creator A5023828025 @default.
- W2078242664 creator A5062530717 @default.
- W2078242664 creator A5071794545 @default.
- W2078242664 date "2000-11-01" @default.
- W2078242664 modified "2023-09-26" @default.
- W2078242664 title "Metabolic and chemical studies on N-(4-chlorobenzyl)-N′-benzoylhydrazine" @default.
- W2078242664 cites W2015735338 @default.
- W2078242664 cites W2037009872 @default.
- W2078242664 cites W2046320940 @default.
- W2078242664 cites W2051246944 @default.
- W2078242664 cites W2056905298 @default.
- W2078242664 cites W2065445082 @default.
- W2078242664 cites W2066300134 @default.
- W2078242664 cites W2204173622 @default.
- W2078242664 cites W2319729310 @default.
- W2078242664 doi "https://doi.org/10.1016/s0014-827x(00)00077-x" @default.
- W2078242664 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11152244" @default.
- W2078242664 hasPublicationYear "2000" @default.
- W2078242664 type Work @default.
- W2078242664 sameAs 2078242664 @default.
- W2078242664 citedByCount "10" @default.
- W2078242664 countsByYear W20782426642013 @default.
- W2078242664 countsByYear W20782426642014 @default.
- W2078242664 countsByYear W20782426642021 @default.
- W2078242664 countsByYear W20782426642023 @default.
- W2078242664 crossrefType "journal-article" @default.
- W2078242664 hasAuthorship W2078242664A5023828025 @default.
- W2078242664 hasAuthorship W2078242664A5062530717 @default.
- W2078242664 hasAuthorship W2078242664A5071794545 @default.
- W2078242664 hasConcept C114373084 @default.
- W2078242664 hasConcept C178790620 @default.
- W2078242664 hasConcept C179998833 @default.
- W2078242664 hasConcept C185592680 @default.
- W2078242664 hasConcept C192989942 @default.
- W2078242664 hasConcept C202751555 @default.
- W2078242664 hasConcept C2776524530 @default.
- W2078242664 hasConcept C2777477808 @default.
- W2078242664 hasConcept C2780263894 @default.
- W2078242664 hasConcept C2780349576 @default.
- W2078242664 hasConcept C2780400988 @default.
- W2078242664 hasConcept C2780471494 @default.
- W2078242664 hasConcept C43617362 @default.
- W2078242664 hasConcept C55493867 @default.
- W2078242664 hasConcept C62231903 @default.
- W2078242664 hasConcept C71240020 @default.
- W2078242664 hasConcept C87644729 @default.
- W2078242664 hasConcept C94412978 @default.
- W2078242664 hasConceptScore W2078242664C114373084 @default.
- W2078242664 hasConceptScore W2078242664C178790620 @default.
- W2078242664 hasConceptScore W2078242664C179998833 @default.
- W2078242664 hasConceptScore W2078242664C185592680 @default.
- W2078242664 hasConceptScore W2078242664C192989942 @default.
- W2078242664 hasConceptScore W2078242664C202751555 @default.
- W2078242664 hasConceptScore W2078242664C2776524530 @default.
- W2078242664 hasConceptScore W2078242664C2777477808 @default.
- W2078242664 hasConceptScore W2078242664C2780263894 @default.
- W2078242664 hasConceptScore W2078242664C2780349576 @default.
- W2078242664 hasConceptScore W2078242664C2780400988 @default.
- W2078242664 hasConceptScore W2078242664C2780471494 @default.
- W2078242664 hasConceptScore W2078242664C43617362 @default.
- W2078242664 hasConceptScore W2078242664C55493867 @default.
- W2078242664 hasConceptScore W2078242664C62231903 @default.
- W2078242664 hasConceptScore W2078242664C71240020 @default.
- W2078242664 hasConceptScore W2078242664C87644729 @default.
- W2078242664 hasConceptScore W2078242664C94412978 @default.
- W2078242664 hasIssue "9-10" @default.
- W2078242664 hasLocation W20782426641 @default.
- W2078242664 hasLocation W20782426642 @default.
- W2078242664 hasOpenAccess W2078242664 @default.
- W2078242664 hasPrimaryLocation W20782426641 @default.
- W2078242664 hasRelatedWork W1589923708 @default.
- W2078242664 hasRelatedWork W1793749036 @default.
- W2078242664 hasRelatedWork W2015972641 @default.
- W2078242664 hasRelatedWork W2020503345 @default.
- W2078242664 hasRelatedWork W2053532436 @default.
- W2078242664 hasRelatedWork W2078242664 @default.
- W2078242664 hasRelatedWork W2087639700 @default.
- W2078242664 hasRelatedWork W2137364341 @default.
- W2078242664 hasRelatedWork W2145731114 @default.
- W2078242664 hasRelatedWork W2292193025 @default.
- W2078242664 hasVolume "55" @default.
- W2078242664 isParatext "false" @default.
- W2078242664 isRetracted "false" @default.
- W2078242664 magId "2078242664" @default.
- W2078242664 workType "article" @default.