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- W2078244673 abstract "The reliability of 2-DE gel-based comparative proteomics is severely impaired by the potential presence of overlapping proteins. We describe a methodological procedure which may solve this problem. Corresponding protein spots from two experimental groups are digested in the presence of 16O and 18O, respectively. Samples are pooled and proteins identified by MS. The 18O/16O-ratios of the different proteins found in the same spot distinguish proteins with altered from those whose intensity is unchanged." @default.
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- W2078244673 date "2009-06-01" @default.
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- W2078244673 title "In-Gel <sup>18</sup>O Labeling for Improved Identification of Proteins from 2-DE Gel Spots in Comparative Proteomic Experiments" @default.
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- W2078244673 doi "https://doi.org/10.1021/pr8010765" @default.
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