Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078245616> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2078245616 endingPage "386" @default.
- W2078245616 startingPage "379" @default.
- W2078245616 abstract "The effects of cyclosporin and prednisone on plasma lipid and lipoprotein levels were studied in 20 allogeneic bone-marrow transplantation patients receiving cyclosporin plus prednisone therapy, and in 14 allogeneic patients treated only with cyclosporin during 100 days. Eighteen autologous bone-marrow patients not requiring cyclosporin were used as a control group. Patients were studied 5 days prior to transplantation, and on days 30, 60, and 100 after transplantation. To determine the reversibility of the changes, lipid parameters were analyzed 30 days after completion of the treatment. Nutritional supplementation, conditioning regimens, and concomitant medications were not significantly different between groups. Furthermore, no significant differences in age, weight, lipid, or lipoprotein levels were found at baseline. Our results indicate that cyclosporin therapy induces a reversible increase of plasma cholesterol, LDL-cholesterol, triglycerides, VLDL-triglycerides, and apolipoprotein B and a decrease of HDL-cholesterol, HDL2-cholesterol, and apolipoprotein A-I. The addition of prednisone to cyclosporin therapy induces a higher increase in plasma cholesterol mainly due to an increase in HDL-cholesterol. Total cholesterol/HDL-cholesterol ratio increased significantly in patients treated only with cyclosporin. No differences were found in this ratio in patients treated with prednisone compared to those submitted to autologous bone-marrow transplantation. Lipid changes observed in this study were reversible 30 days after cessation of cyclosporin treatment." @default.
- W2078245616 created "2016-06-24" @default.
- W2078245616 creator A5004752837 @default.
- W2078245616 creator A5018279960 @default.
- W2078245616 creator A5027327306 @default.
- W2078245616 creator A5027905252 @default.
- W2078245616 creator A5038929704 @default.
- W2078245616 creator A5053271087 @default.
- W2078245616 creator A5063345490 @default.
- W2078245616 creator A5073235477 @default.
- W2078245616 date "1992-10-01" @default.
- W2078245616 modified "2023-10-11" @default.
- W2078245616 title "Effect of cyclosporin on plasma lipoproteins in bone marrow transplantation patients" @default.
- W2078245616 cites W1449253847 @default.
- W2078245616 cites W1970192183 @default.
- W2078245616 cites W1993082334 @default.
- W2078245616 cites W1993442513 @default.
- W2078245616 cites W2015117382 @default.
- W2078245616 cites W2020506085 @default.
- W2078245616 cites W2026959361 @default.
- W2078245616 cites W2031358020 @default.
- W2078245616 cites W2116672383 @default.
- W2078245616 cites W2157219243 @default.
- W2078245616 cites W2189623052 @default.
- W2078245616 cites W2417620455 @default.
- W2078245616 cites W4233292045 @default.
- W2078245616 cites W4246242698 @default.
- W2078245616 cites W4255940022 @default.
- W2078245616 doi "https://doi.org/10.1016/0009-9120(92)80021-8" @default.
- W2078245616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1490302" @default.
- W2078245616 hasPublicationYear "1992" @default.
- W2078245616 type Work @default.
- W2078245616 sameAs 2078245616 @default.
- W2078245616 citedByCount "24" @default.
- W2078245616 countsByYear W20782456162012 @default.
- W2078245616 crossrefType "journal-article" @default.
- W2078245616 hasAuthorship W2078245616A5004752837 @default.
- W2078245616 hasAuthorship W2078245616A5018279960 @default.
- W2078245616 hasAuthorship W2078245616A5027327306 @default.
- W2078245616 hasAuthorship W2078245616A5027905252 @default.
- W2078245616 hasAuthorship W2078245616A5038929704 @default.
- W2078245616 hasAuthorship W2078245616A5053271087 @default.
- W2078245616 hasAuthorship W2078245616A5063345490 @default.
- W2078245616 hasAuthorship W2078245616A5073235477 @default.
- W2078245616 hasConcept C126322002 @default.
- W2078245616 hasConcept C134018914 @default.
- W2078245616 hasConcept C2778163477 @default.
- W2078245616 hasConcept C2778270857 @default.
- W2078245616 hasConcept C2778720950 @default.
- W2078245616 hasConcept C2780007613 @default.
- W2078245616 hasConcept C2780072125 @default.
- W2078245616 hasConcept C2911091166 @default.
- W2078245616 hasConcept C62746215 @default.
- W2078245616 hasConcept C71924100 @default.
- W2078245616 hasConcept C90924648 @default.
- W2078245616 hasConceptScore W2078245616C126322002 @default.
- W2078245616 hasConceptScore W2078245616C134018914 @default.
- W2078245616 hasConceptScore W2078245616C2778163477 @default.
- W2078245616 hasConceptScore W2078245616C2778270857 @default.
- W2078245616 hasConceptScore W2078245616C2778720950 @default.
- W2078245616 hasConceptScore W2078245616C2780007613 @default.
- W2078245616 hasConceptScore W2078245616C2780072125 @default.
- W2078245616 hasConceptScore W2078245616C2911091166 @default.
- W2078245616 hasConceptScore W2078245616C62746215 @default.
- W2078245616 hasConceptScore W2078245616C71924100 @default.
- W2078245616 hasConceptScore W2078245616C90924648 @default.
- W2078245616 hasIssue "5" @default.
- W2078245616 hasLocation W20782456161 @default.
- W2078245616 hasLocation W20782456162 @default.
- W2078245616 hasOpenAccess W2078245616 @default.
- W2078245616 hasPrimaryLocation W20782456161 @default.
- W2078245616 hasRelatedWork W1966967166 @default.
- W2078245616 hasRelatedWork W1981345773 @default.
- W2078245616 hasRelatedWork W1999568358 @default.
- W2078245616 hasRelatedWork W2025648868 @default.
- W2078245616 hasRelatedWork W2035331946 @default.
- W2078245616 hasRelatedWork W2072880852 @default.
- W2078245616 hasRelatedWork W2117255531 @default.
- W2078245616 hasRelatedWork W2157219243 @default.
- W2078245616 hasRelatedWork W2418228134 @default.
- W2078245616 hasRelatedWork W2495016602 @default.
- W2078245616 hasVolume "25" @default.
- W2078245616 isParatext "false" @default.
- W2078245616 isRetracted "false" @default.
- W2078245616 magId "2078245616" @default.
- W2078245616 workType "article" @default.