FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078251181> ?p ?o ?g. }

• W2078251181 endingPage "4433" @default.
• W2078251181 startingPage "4433" @default.
• W2078251181 abstract "A series of amphiphilic cationic methoxy polyethylene glycol-b-poly{N-[3-(dimethylamino)propyl]methacrylamide-co-[2-hydroxylethylmethacrylate-poly(ε-caprolactone)]} {MPEG-b-P[NDAPM-co-(HEMA-PCL)]} polymers were synthesized by combining reversible addition–fragmentation chain transfer (RAFT) polymerization and the macromonomer method. The resulting polymers were able to self-assemble into micelles in water with a critical micellar concentration (CMC) in the range of 10–30 mg L−1 and the CMC increased with the decrease in the PCL block content. It was found that the resulting polymers were able to form electrostatic complexes with plasmid DNA. The polymer–DNA complexes did not show apparent cytotoxicity in 293T cells. Importantly, the complexes exhibited good transfection efficiency in 293T cells at certain N/P ratios, while doxorubicin-loaded polymeric micelles also displayed controlled drug release. Besides, confocal microscopy showed that the drug and gene simultaneously carried by the cationic micelles could be delivered into the same cells, suggesting great potential for achieving the synergistic effect of drug and gene therapies." @default.
• W2078251181 created "2016-06-24" @default.
• W2078251181 creator A5010969293 @default.
• W2078251181 creator A5028406995 @default.
• W2078251181 creator A5038811887 @default.
• W2078251181 creator A5069099639 @default.
• W2078251181 creator A5080257264 @default.
• W2078251181 creator A5083089557 @default.
• W2078251181 date "2008-01-01" @default.
• W2078251181 modified "2023-10-08" @default.
• W2078251181 title "Novel polycationic micelles for drug delivery and gene transfer" @default.
• W2078251181 cites W1970631293 @default.
• W2078251181 cites W1972919234 @default.
• W2078251181 cites W1985631236 @default.
• W2078251181 cites W1994955955 @default.
• W2078251181 cites W2008513470 @default.
• W2078251181 cites W2013311947 @default.
• W2078251181 cites W2016750917 @default.
• W2078251181 cites W2021199477 @default.
• W2078251181 cites W2030556927 @default.
• W2078251181 cites W2031749799 @default.
• W2078251181 cites W2037078276 @default.
• W2078251181 cites W2044072446 @default.
• W2078251181 cites W2044486922 @default.
• W2078251181 cites W2057632167 @default.
• W2078251181 cites W2057848113 @default.
• W2078251181 cites W2064576236 @default.
• W2078251181 cites W2068214938 @default.
• W2078251181 cites W2070484202 @default.
• W2078251181 cites W2086731246 @default.
• W2078251181 cites W2089499711 @default.
• W2078251181 cites W2090127461 @default.
• W2078251181 cites W2090950664 @default.
• W2078251181 cites W2093992205 @default.
• W2078251181 cites W2110688302 @default.
• W2078251181 cites W2127667644 @default.
• W2078251181 cites W2162803403 @default.
• W2078251181 cites W2164833579 @default.
• W2078251181 cites W2167385785 @default.
• W2078251181 cites W2170020824 @default.
• W2078251181 cites W2170311252 @default.
• W2078251181 cites W2170776146 @default.
• W2078251181 cites W4235396474 @default.
• W2078251181 cites W4242601767 @default.
• W2078251181 doi "https://doi.org/10.1039/b801249k" @default.
• W2078251181 hasPublicationYear "2008" @default.
• W2078251181 type Work @default.
• W2078251181 sameAs 2078251181 @default.
• W2078251181 citedByCount "67" @default.
• W2078251181 countsByYear W20782511812012 @default.
• W2078251181 countsByYear W20782511812013 @default.
• W2078251181 countsByYear W20782511812014 @default.
• W2078251181 countsByYear W20782511812015 @default.
• W2078251181 countsByYear W20782511812016 @default.
• W2078251181 countsByYear W20782511812017 @default.
• W2078251181 countsByYear W20782511812018 @default.
• W2078251181 countsByYear W20782511812019 @default.
• W2078251181 countsByYear W20782511812021 @default.
• W2078251181 countsByYear W20782511812022 @default.
• W2078251181 crossrefType "journal-article" @default.
• W2078251181 hasAuthorship W2078251181A5010969293 @default.
• W2078251181 hasAuthorship W2078251181A5028406995 @default.
• W2078251181 hasAuthorship W2078251181A5038811887 @default.
• W2078251181 hasAuthorship W2078251181A5069099639 @default.
• W2078251181 hasAuthorship W2078251181A5080257264 @default.
• W2078251181 hasAuthorship W2078251181A5083089557 @default.
• W2078251181 hasConcept C104317684 @default.
• W2078251181 hasConcept C111998727 @default.
• W2078251181 hasConcept C11268172 @default.
• W2078251181 hasConcept C121120078 @default.
• W2078251181 hasConcept C12554922 @default.
• W2078251181 hasConcept C135983454 @default.
• W2078251181 hasConcept C15920480 @default.
• W2078251181 hasConcept C178790620 @default.
• W2078251181 hasConcept C183882617 @default.
• W2078251181 hasConcept C184651966 @default.
• W2078251181 hasConcept C185592680 @default.
• W2078251181 hasConcept C188027245 @default.
• W2078251181 hasConcept C2775961978 @default.
• W2078251181 hasConcept C2776964284 @default.
• W2078251181 hasConcept C2779402116 @default.
• W2078251181 hasConcept C2779820397 @default.
• W2078251181 hasConcept C34594497 @default.
• W2078251181 hasConcept C44228677 @default.
• W2078251181 hasConcept C521977710 @default.
• W2078251181 hasConcept C54009773 @default.
• W2078251181 hasConcept C55493867 @default.
• W2078251181 hasConcept C67407626 @default.
• W2078251181 hasConcept C86803240 @default.
• W2078251181 hasConcept C9132879 @default.
• W2078251181 hasConceptScore W2078251181C104317684 @default.
• W2078251181 hasConceptScore W2078251181C111998727 @default.
• W2078251181 hasConceptScore W2078251181C11268172 @default.
• W2078251181 hasConceptScore W2078251181C121120078 @default.
• W2078251181 hasConceptScore W2078251181C12554922 @default.
• W2078251181 hasConceptScore W2078251181C135983454 @default.
• W2078251181 hasConceptScore W2078251181C15920480 @default.
• W2078251181 hasConceptScore W2078251181C178790620 @default.

• next