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• W2078269512 abstract "To assess the quality of life of patients with rheumatoid arthritis undergoing out-patient treatment with TNF inhibitors (etanercept and adalimumab). Observational, descriptive, and multi-centre study. A specific validated questionnaire was used (QOL-RA Scale) in its Spanish version, with complete confidentiality ensured. To measure the reliability of the results, the Cronbach alpha coefficient was used. A descriptive analysis was carried out to compare the results obtained with those obtained from studies in the USA and Colombia. A total of 82 patients were selected who mainly consisted of married housewives who had not undergone any previous studies. The average amount of years from diagnosis was 11.81 years (7.30) and the average duration of treatment with TNF inhibitors was 1.71 years (1.03). The results of the questionnaire were: physical ability 5.42 (1.67), pain 5.10 (1.83), social life 7.08 (1.96), support 7.45 (2.10), mood 6.02 (2.03), stress 5.50 (2.01), arthritis 5.15 (1.86), health 5.50 (1.77). The results obtained were similar to those from the USA, although they showed a lower score for mood and stress categories. However, the high score in the support and social-life categories was more similar to that obtained with the Colombian questionnaire. All patients considered their quality of life to have improved with the use of TNF inhibitors. The quality of life in patients with rheumatoid arthritis is low, determined by pain and symptoms of depression. The patients believe that TNF inhibitors have improved their quality of life. Evaluar la calidad de vida en pacientes con artritis reumatoide en tratamiento ambulatorio con anti-TNF (etanercept y adalimumab). Estudio observacional, descriptivo y multicéntrico. Se utilizó un cuestionario específico validado (QOL-RA Scale) en su versión en español, manteniendo la confidencialidad al máximo. Para medir la fiabilidad de los resultados se utilizó el coeficiente alfa de Cronbach. Se ha realizado un análisis descriptivo para comparar los resultados obtenidos con estudios realizados en la población estadounidense y colombiana. Se seleccionaron 82 pacientes. Destacó el perfil de ama de casa, casada y con ningún estudio o estudios primarios. La media de años de diagnóstico fue 11,81 ± 7,30 años y la de tratamiento con anti-TNF fue de 1,71 ± 1,03 años. Los resultados para la encuesta fueron: habilidad física 5,42 ± 1,67), dolor 5,10 ± 1,83, vida social 7,08 ± 1,96, apoyo 7,45 ± 2,10), estado de ánimo 6,02 ± 2,03, tensión nerviosa 5,50 ± 2,01, artritis 5,15 ± 1,86), salud 5,50 ± 1,77. Los resultados obtenidos fueron similares a los encontrados en la población estadounidense, aunque destaca una menor puntuación en el ánimo y la tensión nerviosa. Sin embargo, la alta puntuación en lo referente al apoyo y la vida social fue más parecida a la obtenida en la población colombiana. Todos los pacientes consideraron que su calidad de vida había mejorado con la medicación anti-TNF. La calidad de vida en pacientes con artritis reumatoide es baja, determinada por el dolor y los síntomas depresivos. Los pacientes tienen la percepción de que los anti-TNF han mejorado su calidad de vida." @default.
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• W2078269512 date "2008-01-01" @default.
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• W2078269512 title "Quality of Life of Patients With Rheumatoid Arthritis Undergoing Out-Patient Treatment With TNF Inhibitors" @default.
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• W2078269512 doi "https://doi.org/10.1016/s2173-5085(08)70040-6" @default.
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