Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078271720> ?p ?o ?g. }
- W2078271720 endingPage "9" @default.
- W2078271720 startingPage "1" @default.
- W2078271720 abstract "The antiangiogenesis effect of Ficus carica leaves extract in an air pouch model of inflammation was investigated in rat. Inflammation was induced by injection of carrageenan into pouches. After antioxidant capacity and total phenolic content (TPC) investigations, the extract was administered at 5, 25, and 50 mg/pouch, and then the volume of exudates, the cell number, TNF α , PGE 2 , and VEGF levels were measured. Angiogenesis of granulation tissues was determined by measuring hemoglobin content. Based on the DPPH assay, the extract had significant antioxidant activity with TPC of 11.70 mg GAE/100 g dry sample. In addition, leukocyte accumulation and volume of exudate were significantly inhibited by the extract. Moreover, it significantly decreased the production of TNF α , PGE 2 , and VEGF, while angiogenesis was significantly inhibited by all administered doses. Interestingly, attenuation of angiogenesis and inflammatory parameters (except leukocyte accumulation) by the extract was similar to that shown by diclofenac. The extract has anti-inflammatory effects and ameliorated cell influx and exudation to the site of the inflammatory response which may be related to the local inhibition of TNF α , PGE 2 , and VEGF levels as similarly shown by diclofenac. The antiangiogenesis and anti-VEGF effects of Ficus carica may be correlated with its significant antioxidant potentials." @default.
- W2078271720 created "2016-06-24" @default.
- W2078271720 creator A5008675570 @default.
- W2078271720 creator A5015653562 @default.
- W2078271720 creator A5031219406 @default.
- W2078271720 creator A5035665313 @default.
- W2078271720 creator A5037346265 @default.
- W2078271720 creator A5045095239 @default.
- W2078271720 creator A5081651440 @default.
- W2078271720 date "2015-01-01" @default.
- W2078271720 modified "2023-10-14" @default.
- W2078271720 title "Methanolic Extract of<i>Ficus carica</i>Linn. Leaves Exerts Antiangiogenesis Effects Based on the Rat Air Pouch Model of Inflammation" @default.
- W2078271720 cites W1551337262 @default.
- W2078271720 cites W1873126901 @default.
- W2078271720 cites W1886021042 @default.
- W2078271720 cites W1916024384 @default.
- W2078271720 cites W1965732584 @default.
- W2078271720 cites W1967526789 @default.
- W2078271720 cites W1971855890 @default.
- W2078271720 cites W1980233065 @default.
- W2078271720 cites W1981592867 @default.
- W2078271720 cites W1990068847 @default.
- W2078271720 cites W1995827857 @default.
- W2078271720 cites W2001476006 @default.
- W2078271720 cites W2008932880 @default.
- W2078271720 cites W2016393415 @default.
- W2078271720 cites W2022594313 @default.
- W2078271720 cites W2022809525 @default.
- W2078271720 cites W2024125916 @default.
- W2078271720 cites W2030478014 @default.
- W2078271720 cites W2033537739 @default.
- W2078271720 cites W2042316754 @default.
- W2078271720 cites W2049821417 @default.
- W2078271720 cites W2051001095 @default.
- W2078271720 cites W2055851568 @default.
- W2078271720 cites W2060058623 @default.
- W2078271720 cites W2062694132 @default.
- W2078271720 cites W2064382457 @default.
- W2078271720 cites W2072635353 @default.
- W2078271720 cites W2073768876 @default.
- W2078271720 cites W2079953284 @default.
- W2078271720 cites W2087102885 @default.
- W2078271720 cites W2093402029 @default.
- W2078271720 cites W2125915558 @default.
- W2078271720 cites W2139423543 @default.
- W2078271720 cites W2150285674 @default.
- W2078271720 cites W2150355163 @default.
- W2078271720 cites W2168711492 @default.
- W2078271720 cites W2272602062 @default.
- W2078271720 cites W4234655802 @default.
- W2078271720 doi "https://doi.org/10.1155/2015/760405" @default.
- W2078271720 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4419259" @default.
- W2078271720 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25977699" @default.
- W2078271720 hasPublicationYear "2015" @default.
- W2078271720 type Work @default.
- W2078271720 sameAs 2078271720 @default.
- W2078271720 citedByCount "21" @default.
- W2078271720 countsByYear W20782717202014 @default.
- W2078271720 countsByYear W20782717202016 @default.
- W2078271720 countsByYear W20782717202017 @default.
- W2078271720 countsByYear W20782717202018 @default.
- W2078271720 countsByYear W20782717202019 @default.
- W2078271720 countsByYear W20782717202020 @default.
- W2078271720 countsByYear W20782717202021 @default.
- W2078271720 countsByYear W20782717202022 @default.
- W2078271720 countsByYear W20782717202023 @default.
- W2078271720 crossrefType "journal-article" @default.
- W2078271720 hasAuthorship W2078271720A5008675570 @default.
- W2078271720 hasAuthorship W2078271720A5015653562 @default.
- W2078271720 hasAuthorship W2078271720A5031219406 @default.
- W2078271720 hasAuthorship W2078271720A5035665313 @default.
- W2078271720 hasAuthorship W2078271720A5037346265 @default.
- W2078271720 hasAuthorship W2078271720A5045095239 @default.
- W2078271720 hasAuthorship W2078271720A5081651440 @default.
- W2078271720 hasBestOaLocation W20782717201 @default.
- W2078271720 hasConcept C126322002 @default.
- W2078271720 hasConcept C144027150 @default.
- W2078271720 hasConcept C178790620 @default.
- W2078271720 hasConcept C185592680 @default.
- W2078271720 hasConcept C203014093 @default.
- W2078271720 hasConcept C2776914184 @default.
- W2078271720 hasConcept C2778004101 @default.
- W2078271720 hasConcept C2778284287 @default.
- W2078271720 hasConcept C2779231358 @default.
- W2078271720 hasConcept C2779362140 @default.
- W2078271720 hasConcept C2780394083 @default.
- W2078271720 hasConcept C2781227287 @default.
- W2078271720 hasConcept C519581460 @default.
- W2078271720 hasConcept C55493867 @default.
- W2078271720 hasConcept C556039675 @default.
- W2078271720 hasConcept C59822182 @default.
- W2078271720 hasConcept C71924100 @default.
- W2078271720 hasConcept C86803240 @default.
- W2078271720 hasConcept C98274493 @default.
- W2078271720 hasConceptScore W2078271720C126322002 @default.
- W2078271720 hasConceptScore W2078271720C144027150 @default.
- W2078271720 hasConceptScore W2078271720C178790620 @default.
- W2078271720 hasConceptScore W2078271720C185592680 @default.