FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078272321> ?p ?o ?g. }

• W2078272321 endingPage "21" @default.
• W2078272321 startingPage "12" @default.
• W2078272321 abstract "We report the first voxel-based morphometric (VBM) study to examine cerebral grey and white matter and cerebrospinal fluid (CSF) using computational morphometry in never-medicated, first-episode psychosis (FEP). Region-of-interest (ROI) analysis was also performed blind to group membership. 26 never-medicated individuals with FEP (23 with DSM-IV schizophrenia) and 38 healthy controls had MRI brain scans. Groups were balanced for age, sex, handedness, ethnicity, paternal socio-economic status, and height. Healthy controls were recruited from the local community by advertisement. Grey matter, white matter, and CSF: global brain volume ratios were significantly smaller in patients. Patients had significantly less grey matter volume in L and R caudate nuclei, cingulate gyri, parahippocampal gyri, superior temporal gyri, cerebellum and R thalamus, prefrontal cortex. They also had significantly less white matter volume in the R anterior limb of the internal capsule fronto-occipital fasciculus and L and R fornices, and significantly greater CSF volume especially in the R lateral ventricle. Excluding the 3 subjects with brief psychotic disorder did not alter our results. Our data suggest that fronto-temporal and subcortical-limbic circuits are morphologically abnormal in never-medicated, schizophrenia. ROI analysis comparing the schizophrenia group (n = 23) with the healthy controls (n = 38) confirmed caudate volumes were significantly smaller bilaterally by 11%, and lateral ventricular volume was significantly larger on the right by 26% in the patients. Caudate nuclei and lateral ventricular volume measurements were uncorrelated (Pearson correlation coefficient 0.30, p = 0.10), ruling out the possibility of segmentation artefact. Ratio of lateral ventricle to caudate volume was bilaterally significantly increased (p < 0.005, 2-tailed), which could represent an early biomarker in first-episode, never-medicated schizophrenia." @default.
• W2078272321 created "2016-06-24" @default.
• W2078272321 creator A5004996923 @default.
• W2078272321 creator A5011790360 @default.
• W2078272321 creator A5017135808 @default.
• W2078272321 creator A5025660060 @default.
• W2078272321 creator A5030640570 @default.
• W2078272321 creator A5043352339 @default.
• W2078272321 creator A5053930432 @default.
• W2078272321 creator A5054142205 @default.
• W2078272321 creator A5058898734 @default.
• W2078272321 creator A5064520181 @default.
• W2078272321 creator A5088960112 @default.
• W2078272321 date "2007-01-01" @default.
• W2078272321 modified "2023-10-01" @default.
• W2078272321 title "Cerebral grey, white matter and csf in never-medicated, first-episode schizophrenia" @default.
• W2078272321 cites W177664770 @default.
• W2078272321 cites W1973759448 @default.
• W2078272321 cites W1974608989 @default.
• W2078272321 cites W1975310269 @default.
• W2078272321 cites W1979315240 @default.
• W2078272321 cites W1980763739 @default.
• W2078272321 cites W1984470001 @default.
• W2078272321 cites W1985994929 @default.
• W2078272321 cites W1989083417 @default.
• W2078272321 cites W1999591954 @default.
• W2078272321 cites W2001469430 @default.
• W2078272321 cites W2011228295 @default.
• W2078272321 cites W2013312824 @default.
• W2078272321 cites W2024417178 @default.
• W2078272321 cites W2025429312 @default.
• W2078272321 cites W2028476413 @default.
• W2078272321 cites W2029516410 @default.
• W2078272321 cites W2033251552 @default.
• W2078272321 cites W2051690784 @default.
• W2078272321 cites W2062648684 @default.
• W2078272321 cites W2071092702 @default.
• W2078272321 cites W2079981725 @default.
• W2078272321 cites W2079989484 @default.
• W2078272321 cites W2080081589 @default.
• W2078272321 cites W2083934855 @default.
• W2078272321 cites W2099402149 @default.
• W2078272321 cites W2100173716 @default.
• W2078272321 cites W2103691876 @default.
• W2078272321 cites W2113934269 @default.
• W2078272321 cites W2115113626 @default.
• W2078272321 cites W2116087808 @default.
• W2078272321 cites W2116877426 @default.
• W2078272321 cites W2118421222 @default.
• W2078272321 cites W2121300736 @default.
• W2078272321 cites W2122870641 @default.
• W2078272321 cites W2124588234 @default.
• W2078272321 cites W2124677417 @default.
• W2078272321 cites W2130928508 @default.
• W2078272321 cites W2131552807 @default.
• W2078272321 cites W2151602940 @default.
• W2078272321 cites W2153670274 @default.
• W2078272321 cites W2155752633 @default.
• W2078272321 cites W2156123885 @default.
• W2078272321 cites W2163471335 @default.
• W2078272321 cites W2168100818 @default.
• W2078272321 cites W2170644672 @default.
• W2078272321 cites W2171142865 @default.
• W2078272321 cites W2171652727 @default.
• W2078272321 cites W2333089169 @default.
• W2078272321 doi "https://doi.org/10.1016/j.schres.2006.09.009" @default.
• W2078272321 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17098398" @default.
• W2078272321 hasPublicationYear "2007" @default.
• W2078272321 type Work @default.
• W2078272321 sameAs 2078272321 @default.
• W2078272321 citedByCount "176" @default.
• W2078272321 countsByYear W20782723212012 @default.
• W2078272321 countsByYear W20782723212013 @default.
• W2078272321 countsByYear W20782723212014 @default.
• W2078272321 countsByYear W20782723212015 @default.
• W2078272321 countsByYear W20782723212016 @default.
• W2078272321 countsByYear W20782723212017 @default.
• W2078272321 countsByYear W20782723212018 @default.
• W2078272321 countsByYear W20782723212019 @default.
• W2078272321 countsByYear W20782723212020 @default.
• W2078272321 countsByYear W20782723212021 @default.
• W2078272321 countsByYear W20782723212022 @default.
• W2078272321 countsByYear W20782723212023 @default.
• W2078272321 crossrefType "journal-article" @default.
• W2078272321 hasAuthorship W2078272321A5004996923 @default.
• W2078272321 hasAuthorship W2078272321A5011790360 @default.
• W2078272321 hasAuthorship W2078272321A5017135808 @default.
• W2078272321 hasAuthorship W2078272321A5025660060 @default.
• W2078272321 hasAuthorship W2078272321A5030640570 @default.
• W2078272321 hasAuthorship W2078272321A5043352339 @default.
• W2078272321 hasAuthorship W2078272321A5053930432 @default.
• W2078272321 hasAuthorship W2078272321A5054142205 @default.
• W2078272321 hasAuthorship W2078272321A5058898734 @default.
• W2078272321 hasAuthorship W2078272321A5064520181 @default.
• W2078272321 hasAuthorship W2078272321A5088960112 @default.
• W2078272321 hasConcept C118552586 @default.
• W2078272321 hasConcept C126838900 @default.
• W2078272321 hasConcept C143409427 @default.

• next