FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078274249> ?p ?o ?g. }

• W2078274249 endingPage "1115" @default.
• W2078274249 startingPage "1110" @default.
• W2078274249 abstract "Computer simulations of the supercoiling of DNA, largely limited to stochastic search techniques, can offer important information to complement analytical models and experimental data. Through association of an energy function, minimum-energy supercoiled conformations, fluctuations about these states, and interconversions among forms may be sought. In theory, the observation of such large-scale conformational changes is possible, but modeling and numerical considerations limit the picture obtained in practice. A new computational approach is reported that combines an idealized elastic energy model, a compact B-spline representation of circular duplex DNA, and deterministic minimization and molecular dynamics algorithms. A trefoil knotting result, made possible by a large time-step dynamics scheme, is described. The simulated strand passage supports and details a supercoiled-directed knotting mechanism. This process may be associated with collective bending and twisting motions involved in supercoiling propagation and interwound branching. The results also demonstrate the potential effectiveness of the Langevin/implicit-Euler dynamics scheme for studying biomolecular folding and reactions over biologically interesting time scales." @default.
• W2078274249 created "2016-06-24" @default.
• W2078274249 creator A5046513501 @default.
• W2078274249 creator A5060529789 @default.
• W2078274249 date "1992-08-21" @default.
• W2078274249 modified "2023-10-15" @default.
• W2078274249 title "Trefoil Knotting Revealed by Molecular Dynamics Simulations of Supercoiled DNA" @default.
• W2078274249 cites W1497445549 @default.
• W2078274249 cites W1520269335 @default.
• W2078274249 cites W1554799785 @default.
• W2078274249 cites W1581614904 @default.
• W2078274249 cites W1966612732 @default.
• W2078274249 cites W1972146970 @default.
• W2078274249 cites W1974938535 @default.
• W2078274249 cites W1975803620 @default.
• W2078274249 cites W1976312699 @default.
• W2078274249 cites W1981581896 @default.
• W2078274249 cites W1982250810 @default.
• W2078274249 cites W1989980582 @default.
• W2078274249 cites W1995039719 @default.
• W2078274249 cites W1997716297 @default.
• W2078274249 cites W1998081080 @default.
• W2078274249 cites W2004417760 @default.
• W2078274249 cites W2005409698 @default.
• W2078274249 cites W2007583946 @default.
• W2078274249 cites W2012083162 @default.
• W2078274249 cites W2024222447 @default.
• W2078274249 cites W2026326554 @default.
• W2078274249 cites W2037612112 @default.
• W2078274249 cites W2045454144 @default.
• W2078274249 cites W2049327026 @default.
• W2078274249 cites W2055555040 @default.
• W2078274249 cites W2057790203 @default.
• W2078274249 cites W2060268336 @default.
• W2078274249 cites W2061475638 @default.
• W2078274249 cites W2074123165 @default.
• W2078274249 cites W2074485724 @default.
• W2078274249 cites W2074651320 @default.
• W2078274249 cites W2083179556 @default.
• W2078274249 cites W2090783513 @default.
• W2078274249 cites W2091891883 @default.
• W2078274249 cites W2092119508 @default.
• W2078274249 cites W2105107879 @default.
• W2078274249 cites W2106318953 @default.
• W2078274249 cites W2116877934 @default.
• W2078274249 cites W2151938785 @default.
• W2078274249 cites W2158275234 @default.
• W2078274249 cites W2174021414 @default.
• W2078274249 cites W2401089320 @default.
• W2078274249 cites W247911691 @default.
• W2078274249 cites W4231891515 @default.
• W2078274249 cites W4233567369 @default.
• W2078274249 cites W4256439663 @default.
• W2078274249 doi "https://doi.org/10.1126/science.257.5073.1110" @default.
• W2078274249 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1509261" @default.
• W2078274249 hasPublicationYear "1992" @default.
• W2078274249 type Work @default.
• W2078274249 sameAs 2078274249 @default.
• W2078274249 citedByCount "105" @default.
• W2078274249 countsByYear W20782742492012 @default.
• W2078274249 countsByYear W20782742492013 @default.
• W2078274249 countsByYear W20782742492014 @default.
• W2078274249 countsByYear W20782742492015 @default.
• W2078274249 countsByYear W20782742492016 @default.
• W2078274249 countsByYear W20782742492017 @default.
• W2078274249 countsByYear W20782742492018 @default.
• W2078274249 countsByYear W20782742492019 @default.
• W2078274249 countsByYear W20782742492020 @default.
• W2078274249 countsByYear W20782742492021 @default.
• W2078274249 countsByYear W20782742492022 @default.
• W2078274249 crossrefType "journal-article" @default.
• W2078274249 hasAuthorship W2078274249A5046513501 @default.
• W2078274249 hasAuthorship W2078274249A5060529789 @default.
• W2078274249 hasConcept C119599485 @default.
• W2078274249 hasConcept C119621388 @default.
• W2078274249 hasConcept C121332964 @default.
• W2078274249 hasConcept C121864883 @default.
• W2078274249 hasConcept C127413603 @default.
• W2078274249 hasConcept C14961307 @default.
• W2078274249 hasConcept C158456008 @default.
• W2078274249 hasConcept C185592680 @default.
• W2078274249 hasConcept C186060115 @default.
• W2078274249 hasConcept C2776545253 @default.
• W2078274249 hasConcept C2780004032 @default.
• W2078274249 hasConcept C41008148 @default.
• W2078274249 hasConcept C552990157 @default.
• W2078274249 hasConcept C55493867 @default.
• W2078274249 hasConcept C59593255 @default.
• W2078274249 hasConcept C62520636 @default.
• W2078274249 hasConcept C73573662 @default.
• W2078274249 hasConcept C74650414 @default.
• W2078274249 hasConcept C86803240 @default.
• W2078274249 hasConcept C97355855 @default.
• W2078274249 hasConceptScore W2078274249C119599485 @default.
• W2078274249 hasConceptScore W2078274249C119621388 @default.
• W2078274249 hasConceptScore W2078274249C121332964 @default.
• W2078274249 hasConceptScore W2078274249C121864883 @default.
• W2078274249 hasConceptScore W2078274249C127413603 @default.

• next