Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078292917> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2078292917 endingPage "30" @default.
- W2078292917 startingPage "23" @default.
- W2078292917 abstract "This paper assesses the effectiveness of aerosolized tobramycin (TOBI) on cystic fibrosis (CF) lung disease, using a radiologic tool. The published tool, the age-based severity curve (ABS), is derived from Brasfield scoring of chest X-rays (CXR). This study evaluates both the usefulness of the ABS as an assessment tool and the effectiveness of TOBI. Thirty-eight patients were treated with TOBI. Twenty-four treated with dornase alfa were excluded. Fourteen patients, aged 2 months to 22 years (mean, 17 months of TOBI treatment), comprised the study group. Radiographs were obtained over a mean of 7.8 years (SD = 6.5 years; range, 9 months–18 years). Two hundred and eighty-two CXR of TOBI patients were analyzed following the ABS protocol. Rate of decline in radiologic status of the TOBI group and ABS were compared. Also, TOBI was assessed by comparing rate of decline before and after initiation of treatment. The TOBI group's radiologic assessment was compared to its rate of decline in pulmonary function studies and published population data. Rate of decline in ABS was 0.175 Brasfield points/year vs. 0.150 points/year in the TOBI group (P < 0.001). Before treatment, the TOBI group's rate of decline was 0.169 Brasfield points/year; after treatment, it was 0.150 points/year (P = 0.02). Forced vital capacity revealed a statistically significant slowing in rate of decline on TOBI. Although not statistically significant, rate of decline in forced expiratory volume at 1 sec showed a similar trend. The degree of slowing in decline is similar to that previously reported for pulmonary function studies. Pediatr Pulmonol. 2004; 38:23–30. © 2004 Wiley-Liss, Inc." @default.
- W2078292917 created "2016-06-24" @default.
- W2078292917 creator A5012245154 @default.
- W2078292917 creator A5029802394 @default.
- W2078292917 creator A5034509516 @default.
- W2078292917 creator A5041972769 @default.
- W2078292917 date "2004-01-01" @default.
- W2078292917 modified "2023-09-24" @default.
- W2078292917 title "CF: An X-ray database to assess effect of aerosolized tobramycin" @default.
- W2078292917 cites W1897760827 @default.
- W2078292917 cites W1974128924 @default.
- W2078292917 cites W1986108334 @default.
- W2078292917 cites W1989534031 @default.
- W2078292917 cites W1990676990 @default.
- W2078292917 cites W1990987230 @default.
- W2078292917 cites W1993207965 @default.
- W2078292917 cites W2001878860 @default.
- W2078292917 cites W2012105431 @default.
- W2078292917 cites W2028502510 @default.
- W2078292917 cites W2030631267 @default.
- W2078292917 cites W2032940647 @default.
- W2078292917 cites W2036001221 @default.
- W2078292917 cites W2056934536 @default.
- W2078292917 cites W2064279221 @default.
- W2078292917 cites W2074509733 @default.
- W2078292917 cites W2082246284 @default.
- W2078292917 cites W2094301911 @default.
- W2078292917 cites W2113774097 @default.
- W2078292917 cites W2133055199 @default.
- W2078292917 cites W2135602734 @default.
- W2078292917 cites W2142443730 @default.
- W2078292917 cites W2150399236 @default.
- W2078292917 cites W2163575531 @default.
- W2078292917 cites W2165434242 @default.
- W2078292917 cites W2317332612 @default.
- W2078292917 cites W2333398204 @default.
- W2078292917 cites W2336210752 @default.
- W2078292917 doi "https://doi.org/10.1002/ppul.20032" @default.
- W2078292917 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15170870" @default.
- W2078292917 hasPublicationYear "2004" @default.
- W2078292917 type Work @default.
- W2078292917 sameAs 2078292917 @default.
- W2078292917 citedByCount "14" @default.
- W2078292917 countsByYear W20782929172012 @default.
- W2078292917 countsByYear W20782929172013 @default.
- W2078292917 countsByYear W20782929172014 @default.
- W2078292917 countsByYear W20782929172015 @default.
- W2078292917 countsByYear W20782929172019 @default.
- W2078292917 crossrefType "journal-article" @default.
- W2078292917 hasAuthorship W2078292917A5012245154 @default.
- W2078292917 hasAuthorship W2078292917A5029802394 @default.
- W2078292917 hasAuthorship W2078292917A5034509516 @default.
- W2078292917 hasAuthorship W2078292917A5041972769 @default.
- W2078292917 hasConcept C126322002 @default.
- W2078292917 hasConcept C141071460 @default.
- W2078292917 hasConcept C71924100 @default.
- W2078292917 hasConceptScore W2078292917C126322002 @default.
- W2078292917 hasConceptScore W2078292917C141071460 @default.
- W2078292917 hasConceptScore W2078292917C71924100 @default.
- W2078292917 hasIssue "1" @default.
- W2078292917 hasLocation W20782929171 @default.
- W2078292917 hasLocation W20782929172 @default.
- W2078292917 hasOpenAccess W2078292917 @default.
- W2078292917 hasPrimaryLocation W20782929171 @default.
- W2078292917 hasRelatedWork W2002120878 @default.
- W2078292917 hasRelatedWork W2003938723 @default.
- W2078292917 hasRelatedWork W2047967234 @default.
- W2078292917 hasRelatedWork W2118496982 @default.
- W2078292917 hasRelatedWork W2364998975 @default.
- W2078292917 hasRelatedWork W2369162477 @default.
- W2078292917 hasRelatedWork W2439875401 @default.
- W2078292917 hasRelatedWork W4238867864 @default.
- W2078292917 hasRelatedWork W2519357708 @default.
- W2078292917 hasRelatedWork W2525756941 @default.
- W2078292917 hasVolume "38" @default.
- W2078292917 isParatext "false" @default.
- W2078292917 isRetracted "false" @default.
- W2078292917 magId "2078292917" @default.
- W2078292917 workType "article" @default.