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- W2078294505 abstract "Abstract In Day 10 decidualized pseudopregnant rats fed dinoseb in the diet from Days 6 through 9 of pseudopregnancy, uterine wet weight was reduced in the groups fed 100 to 750 ppm (the highest dose tested). Uterine protein and glycogen concentrations in these animals were reduced in a dose-related manner. In Day 16 pregnant rats, orally fed dinoseb from Days 6 through 15 of pregnancy, placental protein and glycogen concentrations were diminished at 200 ppm and greater. Pregnant rats fed dinoseb (Days 6–16) showed reductions in their embryonic survival rates at 200 ppm and greater. The fetal survival rates at birth, from pregnant rats which were similarly administered dinoseb, were reduced at 150 ppm and greater. Fetal weight of fetuses from dams given dinoseb (200 ppm) was diminished. These results from decidualized pseudopregnant and pregnant rats indicate a toxic role for dinoseb in the intrauterine environment. This toxicity is apparently responsible for a decline in fertility in pregnant rats. Moreover, 200 ppm dinoseb seems to be reproductively critical." @default.
- W2078294505 created "2016-06-24" @default.
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- W2078294505 date "1982-10-01" @default.
- W2078294505 modified "2023-09-23" @default.
- W2078294505 title "Reproductive toxicity in pseudopregnant and pregnant rats following postimplantational exposure: Effects of the herbicide dinoseb" @default.
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- W2078294505 doi "https://doi.org/10.1016/0048-3575(82)90100-6" @default.
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