Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078298730> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2078298730 endingPage "81" @default.
- W2078298730 startingPage "76" @default.
- W2078298730 abstract "Patients with acute lymphoblastic leukaemia (ALL) after cytotoxic chemotherapy or haematopoietic stem cell transplantation (HSCT) are at risk for life-threatening invasive fungal disease (IFD). The aim was to evaluate the characteristics, antifungal therapy and outcome of adult patients with ALL after chemotherapy or HSCT receiving caspofungin empirically in a clinical setting. Retrospective chart reviews were conducted at nine large tertiary care centres in Germany. Adult patients with ALL treated empirically with caspofungin according to the product label between 2006 and 2012 were eligible. Data were extracted as case reports. In total, 25 patients (12 males, 13 females; median age 37 years; 19 with B-ALL, 6 with T-ALL) with 28 treatment episodes because of suspected IFD (18 episodes after chemotherapy, 10 episodes after allogeneic HSCT) were included in the analysis. Empirical caspofungin therapy (median duration: 19 days, range 1-105 days) was given as first-line monotherapy in 20 (71.4%), second-line monotherapy in five (17.9%) and combination therapy in three (10.7%) episodes respectively. Therapy rated successful according to the physician's overall assessment (inflammatory parameters, clinical symptoms): 20 (95%) of 21 evaluable episodes with therapy duration of at least 8 days. Empirical caspofungin appears to be an effective therapeutic option in critically ill adult ALL patients with suspected IFD in clinical practice." @default.
- W2078298730 created "2016-06-24" @default.
- W2078298730 creator A5047732907 @default.
- W2078298730 creator A5048939350 @default.
- W2078298730 creator A5063647828 @default.
- W2078298730 creator A5084241424 @default.
- W2078298730 date "2015-01-15" @default.
- W2078298730 modified "2023-10-17" @default.
- W2078298730 title "Empirical caspofungin therapy in clinical practice for suspected invasive fungal disease in adults with acute lymphoblastic leukaemia" @default.
- W2078298730 cites W1640272289 @default.
- W2078298730 cites W1966822398 @default.
- W2078298730 cites W1981025594 @default.
- W2078298730 cites W2012552495 @default.
- W2078298730 cites W2051665742 @default.
- W2078298730 cites W2097394217 @default.
- W2078298730 cites W2114340167 @default.
- W2078298730 cites W2118169480 @default.
- W2078298730 cites W2120631087 @default.
- W2078298730 cites W2123114992 @default.
- W2078298730 cites W2135840745 @default.
- W2078298730 cites W2138460199 @default.
- W2078298730 cites W2140134181 @default.
- W2078298730 cites W2141972408 @default.
- W2078298730 cites W2145822190 @default.
- W2078298730 cites W2151483063 @default.
- W2078298730 cites W2152583091 @default.
- W2078298730 cites W2158382206 @default.
- W2078298730 cites W2163773890 @default.
- W2078298730 cites W2166734004 @default.
- W2078298730 cites W2416430600 @default.
- W2078298730 cites W4376542656 @default.
- W2078298730 doi "https://doi.org/10.1111/myc.12277" @default.
- W2078298730 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25590660" @default.
- W2078298730 hasPublicationYear "2015" @default.
- W2078298730 type Work @default.
- W2078298730 sameAs 2078298730 @default.
- W2078298730 citedByCount "0" @default.
- W2078298730 crossrefType "journal-article" @default.
- W2078298730 hasAuthorship W2078298730A5047732907 @default.
- W2078298730 hasAuthorship W2078298730A5048939350 @default.
- W2078298730 hasAuthorship W2078298730A5063647828 @default.
- W2078298730 hasAuthorship W2078298730A5084241424 @default.
- W2078298730 hasConcept C126322002 @default.
- W2078298730 hasConcept C16005928 @default.
- W2078298730 hasConcept C167135981 @default.
- W2078298730 hasConcept C187212893 @default.
- W2078298730 hasConcept C203014093 @default.
- W2078298730 hasConcept C2776391196 @default.
- W2078298730 hasConcept C2776694085 @default.
- W2078298730 hasConcept C2777408962 @default.
- W2078298730 hasConcept C2779134260 @default.
- W2078298730 hasConcept C2779548794 @default.
- W2078298730 hasConcept C2779629538 @default.
- W2078298730 hasConcept C2780402444 @default.
- W2078298730 hasConcept C71924100 @default.
- W2078298730 hasConceptScore W2078298730C126322002 @default.
- W2078298730 hasConceptScore W2078298730C16005928 @default.
- W2078298730 hasConceptScore W2078298730C167135981 @default.
- W2078298730 hasConceptScore W2078298730C187212893 @default.
- W2078298730 hasConceptScore W2078298730C203014093 @default.
- W2078298730 hasConceptScore W2078298730C2776391196 @default.
- W2078298730 hasConceptScore W2078298730C2776694085 @default.
- W2078298730 hasConceptScore W2078298730C2777408962 @default.
- W2078298730 hasConceptScore W2078298730C2779134260 @default.
- W2078298730 hasConceptScore W2078298730C2779548794 @default.
- W2078298730 hasConceptScore W2078298730C2779629538 @default.
- W2078298730 hasConceptScore W2078298730C2780402444 @default.
- W2078298730 hasConceptScore W2078298730C71924100 @default.
- W2078298730 hasIssue "2" @default.
- W2078298730 hasLocation W20782987301 @default.
- W2078298730 hasLocation W20782987302 @default.
- W2078298730 hasOpenAccess W2078298730 @default.
- W2078298730 hasPrimaryLocation W20782987301 @default.
- W2078298730 hasRelatedWork W2005803431 @default.
- W2078298730 hasRelatedWork W2017140609 @default.
- W2078298730 hasRelatedWork W2043094076 @default.
- W2078298730 hasRelatedWork W2074215323 @default.
- W2078298730 hasRelatedWork W2148051102 @default.
- W2078298730 hasRelatedWork W2166501477 @default.
- W2078298730 hasRelatedWork W2205653230 @default.
- W2078298730 hasRelatedWork W2295557345 @default.
- W2078298730 hasRelatedWork W2371654339 @default.
- W2078298730 hasRelatedWork W4362470491 @default.
- W2078298730 hasVolume "58" @default.
- W2078298730 isParatext "false" @default.
- W2078298730 isRetracted "false" @default.
- W2078298730 magId "2078298730" @default.
- W2078298730 workType "article" @default.