Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078300727> ?p ?o ?g. }
- W2078300727 endingPage "290" @default.
- W2078300727 startingPage "281" @default.
- W2078300727 abstract "15-lipoxygenase (LOX) expression is translationally silenced in early erythroid precursor cells by a specific mRNA-protein complex formed between the differentiation control element in the 3' untranslated region (UTR) and hnRNPs K and E1. The 3'UTR regulatory complex prevents translation initiation by an unknown mechanism. We demonstrate that the 40S ribosomal subunit can be recruited and scan to the translation initiation codon even when the silencing complex is bound to the 3'UTR. However, the joining of the 60S ribosomal subunit at the AUG codon to form a translation competent 80S ribosome is inhibited, unless initiation is mediated by the IGR-IRES of the cricket paralysis virus. These findings identify the critical step at which LOX mRNA translation is controlled and reveal that 60S subunit joining can be specifically regulated." @default.
- W2078300727 created "2016-06-24" @default.
- W2078300727 creator A5000270755 @default.
- W2078300727 creator A5025654264 @default.
- W2078300727 creator A5058116799 @default.
- W2078300727 creator A5077190182 @default.
- W2078300727 date "2001-01-01" @default.
- W2078300727 modified "2023-10-08" @default.
- W2078300727 title "Lipoxygenase mRNA Silencing in Erythroid Differentiation" @default.
- W2078300727 cites W1542686183 @default.
- W2078300727 cites W1554349566 @default.
- W2078300727 cites W1562310953 @default.
- W2078300727 cites W1596577620 @default.
- W2078300727 cites W1788436564 @default.
- W2078300727 cites W1920555941 @default.
- W2078300727 cites W1965199529 @default.
- W2078300727 cites W1972127938 @default.
- W2078300727 cites W1973433187 @default.
- W2078300727 cites W1974717031 @default.
- W2078300727 cites W1981001162 @default.
- W2078300727 cites W1998334193 @default.
- W2078300727 cites W1999765420 @default.
- W2078300727 cites W2020721543 @default.
- W2078300727 cites W2036598706 @default.
- W2078300727 cites W2037485695 @default.
- W2078300727 cites W2068558331 @default.
- W2078300727 cites W2069930342 @default.
- W2078300727 cites W2070404387 @default.
- W2078300727 cites W2078097149 @default.
- W2078300727 cites W2086842428 @default.
- W2078300727 cites W2096733041 @default.
- W2078300727 cites W2104947461 @default.
- W2078300727 cites W2109009498 @default.
- W2078300727 cites W2111760870 @default.
- W2078300727 cites W2112459919 @default.
- W2078300727 cites W2113031608 @default.
- W2078300727 cites W2119031123 @default.
- W2078300727 cites W2122767802 @default.
- W2078300727 cites W2123742352 @default.
- W2078300727 cites W2124269203 @default.
- W2078300727 cites W2142282262 @default.
- W2078300727 cites W2142452471 @default.
- W2078300727 cites W2144081638 @default.
- W2078300727 cites W2157497892 @default.
- W2078300727 cites W2160334805 @default.
- W2078300727 cites W2168757038 @default.
- W2078300727 cites W2168847939 @default.
- W2078300727 cites W2169071084 @default.
- W2078300727 cites W233265278 @default.
- W2078300727 cites W233806587 @default.
- W2078300727 cites W252784604 @default.
- W2078300727 cites W4213326248 @default.
- W2078300727 cites W70018918 @default.
- W2078300727 doi "https://doi.org/10.1016/s0092-8674(01)00212-4" @default.
- W2078300727 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11207368" @default.
- W2078300727 hasPublicationYear "2001" @default.
- W2078300727 type Work @default.
- W2078300727 sameAs 2078300727 @default.
- W2078300727 citedByCount "240" @default.
- W2078300727 countsByYear W20783007272012 @default.
- W2078300727 countsByYear W20783007272013 @default.
- W2078300727 countsByYear W20783007272014 @default.
- W2078300727 countsByYear W20783007272015 @default.
- W2078300727 countsByYear W20783007272016 @default.
- W2078300727 countsByYear W20783007272017 @default.
- W2078300727 countsByYear W20783007272018 @default.
- W2078300727 countsByYear W20783007272019 @default.
- W2078300727 countsByYear W20783007272020 @default.
- W2078300727 countsByYear W20783007272021 @default.
- W2078300727 countsByYear W20783007272022 @default.
- W2078300727 countsByYear W20783007272023 @default.
- W2078300727 crossrefType "journal-article" @default.
- W2078300727 hasAuthorship W2078300727A5000270755 @default.
- W2078300727 hasAuthorship W2078300727A5025654264 @default.
- W2078300727 hasAuthorship W2078300727A5058116799 @default.
- W2078300727 hasAuthorship W2078300727A5077190182 @default.
- W2078300727 hasBestOaLocation W20783007271 @default.
- W2078300727 hasConcept C104292427 @default.
- W2078300727 hasConcept C104317684 @default.
- W2078300727 hasConcept C105580179 @default.
- W2078300727 hasConcept C114847915 @default.
- W2078300727 hasConcept C119056186 @default.
- W2078300727 hasConcept C12464233 @default.
- W2078300727 hasConcept C149364088 @default.
- W2078300727 hasConcept C153911025 @default.
- W2078300727 hasConcept C39685955 @default.
- W2078300727 hasConcept C4718897 @default.
- W2078300727 hasConcept C54355233 @default.
- W2078300727 hasConcept C77430603 @default.
- W2078300727 hasConcept C86803240 @default.
- W2078300727 hasConcept C89604277 @default.
- W2078300727 hasConcept C95444343 @default.
- W2078300727 hasConcept C97154109 @default.
- W2078300727 hasConceptScore W2078300727C104292427 @default.
- W2078300727 hasConceptScore W2078300727C104317684 @default.
- W2078300727 hasConceptScore W2078300727C105580179 @default.
- W2078300727 hasConceptScore W2078300727C114847915 @default.
- W2078300727 hasConceptScore W2078300727C119056186 @default.