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- W2078312269 abstract "ABSTRACT Corneocyte counting is a method for quantitation and visualization of the desquamating portion of the human stratum corneum. The desquamating portion is removed by rubbing the surface in a detergent solution. The cells are dispersed by detergency and mechanical shaking, stained with an aniline dye mixture and counted in a hemocytometer. Glabrous skin gives a count of 10 5 cells per sq cm, plantar and scalp counts are higher and forehead skin is significantly lower. In dandruff the scalp count is nearly twice as great as in normal subjects and exceeds three times the normal value in clinically severe cases. High counts are also found from lesions of psoriasis. In addition to enumeration of the total epithelial cell count the proportion of parakeratotic cells can be assessed. Glabrous areas show 2% or less parakeratotic cells, the forehead 9.9% and normal scalp 16%. In dandruff the proportion exceeds 25% while in psoriatic lesions up to 60% of parakeratotic cells are present. Some evidence on the depth organization of the horny layer is possible by serial sampling at the same spot." @default.
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- W2078312269 date "1969-08-01" @default.
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- W2078312269 title "A Method for Visualizing and Quantitating the Desquamating Portion of the Human Stratum Corneum**From the Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104." @default.
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- W2078312269 doi "https://doi.org/10.1038/jid.1969.115" @default.
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