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• W2078320987 abstract "Alimentary mucositis is a major dose-limiting toxicity associated with anticancer treatment. It is responsible for reducing patient quality of life and represents a significant economic burden in oncology. The pathobiology of alimentary mucositis is extremely complex, and an increased understanding of mechanisms and pathway interactions is required to rationally design improved therapies. This review describes the latest advances in defining mechanisms of alimentary mucositis pathobiology in the context of pathway activation. It focuses particularly on the recent genome-wide analyses of regimen-related mucosal injury and the identification of specific regulatory pathways implicated in mucositis development. This review also discusses the currently known alimentary mucositis risk factors and the development of novel treatments. Suggestions for future research directions have been raised." @default.
• W2078320987 created "2016-06-24" @default.
• W2078320987 creator A5015659735 @default.
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• W2078320987 date "2008-01-01" @default.
• W2078320987 modified "2023-09-27" @default.
• W2078320987 title "New Pathways for Alimentary Mucositis" @default.
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• W2078320987 doi "https://doi.org/10.1155/2008/907892" @default.
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