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- W2078325900 abstract "Chronic wound pathogenic biofilms are host-pathogen environments that colonize and exist as a cohabitation of many bacterial species. These bacterial populations cooperate to promote their own survival and the chronic nature of the infection. Few studies have performed extensive surveys of the bacterial populations that occur within different types of chronic wound biofilms. The use of 3 separate16S-based molecular amplifications followed by pyrosequencing, shotgun Sanger sequencing, and denaturing gradient gel electrophoresis were utilized to survey the major populations of bacteria that occur in the pathogenic biofilms of three types of chronic wound types: diabetic foot ulcers (D), venous leg ulcers (V), and pressure ulcers (P).There are specific major populations of bacteria that were evident in the biofilms of all chronic wound types, including Staphylococcus, Pseudomonas, Peptoniphilus, Enterobacter, Stenotrophomonas, Finegoldia, and Serratia spp. Each of the wound types reveals marked differences in bacterial populations, such as pressure ulcers in which 62% of the populations were identified as obligate anaerobes. There were also populations of bacteria that were identified but not recognized as wound pathogens, such as Abiotrophia para-adiacens and Rhodopseudomonas spp. Results of molecular analyses were also compared to those obtained using traditional culture-based diagnostics. Only in one wound type did culture methods correctly identify the primary bacterial population indicating the need for improved diagnostic methods.If clinicians can gain a better understanding of the wound's microbiota, it will give them a greater understanding of the wound's ecology and will allow them to better manage healing of the wound improving the prognosis of patients. This research highlights the necessity to begin evaluating, studying, and treating chronic wound pathogenic biofilms as multi-species entities in order to improve the outcomes of patients. This survey will also foster the pioneering and development of new molecular diagnostic tools, which can be used to identify the community compositions of chronic wound pathogenic biofilms and other medical biofilm infections." @default.
- W2078325900 created "2016-06-24" @default.
- W2078325900 creator A5006029258 @default.
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- W2078325900 date "2008-01-01" @default.
- W2078325900 modified "2023-10-10" @default.
- W2078325900 title "Survey of bacterial diversity in chronic wounds using Pyrosequencing, DGGE, and full ribosome shotgun sequencing" @default.
- W2078325900 cites W125146514 @default.
- W2078325900 cites W1500073316 @default.
- W2078325900 cites W1532719057 @default.
- W2078325900 cites W1532810787 @default.
- W2078325900 cites W1552589286 @default.
- W2078325900 cites W1667056285 @default.
- W2078325900 cites W168206613 @default.
- W2078325900 cites W174387285 @default.
- W2078325900 cites W1769652070 @default.
- W2078325900 cites W1851197753 @default.
- W2078325900 cites W1900149929 @default.
- W2078325900 cites W1921780704 @default.
- W2078325900 cites W1943592367 @default.
- W2078325900 cites W1964942495 @default.
- W2078325900 cites W1965006954 @default.
- W2078325900 cites W1966037217 @default.
- W2078325900 cites W1967682820 @default.
- W2078325900 cites W1972546694 @default.
- W2078325900 cites W1973216071 @default.
- W2078325900 cites W1973273525 @default.
- W2078325900 cites W1973385753 @default.
- W2078325900 cites W1981602401 @default.
- W2078325900 cites W1983915827 @default.
- W2078325900 cites W1985311973 @default.
- W2078325900 cites W1987614538 @default.
- W2078325900 cites W1989179952 @default.
- W2078325900 cites W1997072938 @default.
- W2078325900 cites W1997714727 @default.
- W2078325900 cites W1998300881 @default.
- W2078325900 cites W1999334990 @default.
- W2078325900 cites W1999466692 @default.
- W2078325900 cites W2001442964 @default.
- W2078325900 cites W2001566296 @default.
- W2078325900 cites W2005015095 @default.
- W2078325900 cites W2005187240 @default.
- W2078325900 cites W2005717715 @default.
- W2078325900 cites W2011836505 @default.
- W2078325900 cites W2014813851 @default.
- W2078325900 cites W2015606968 @default.
- W2078325900 cites W2015783448 @default.
- W2078325900 cites W2016379103 @default.
- W2078325900 cites W2024102323 @default.
- W2078325900 cites W2027966311 @default.
- W2078325900 cites W2032678548 @default.
- W2078325900 cites W2034170472 @default.
- W2078325900 cites W2034224562 @default.
- W2078325900 cites W2037457710 @default.
- W2078325900 cites W2038824708 @default.
- W2078325900 cites W2042307736 @default.
- W2078325900 cites W2042447089 @default.
- W2078325900 cites W2043110296 @default.
- W2078325900 cites W2044958084 @default.
- W2078325900 cites W2048602281 @default.
- W2078325900 cites W2050421878 @default.
- W2078325900 cites W2053404797 @default.
- W2078325900 cites W2056413771 @default.
- W2078325900 cites W2057607409 @default.
- W2078325900 cites W2057691852 @default.
- W2078325900 cites W2058365382 @default.
- W2078325900 cites W2061823596 @default.
- W2078325900 cites W2061915063 @default.
- W2078325900 cites W2066631974 @default.
- W2078325900 cites W2067665219 @default.
- W2078325900 cites W2068217910 @default.
- W2078325900 cites W2077860424 @default.
- W2078325900 cites W2082199163 @default.
- W2078325900 cites W2087560225 @default.
- W2078325900 cites W2088493848 @default.
- W2078325900 cites W2090746933 @default.
- W2078325900 cites W2091651320 @default.
- W2078325900 cites W2092135597 @default.
- W2078325900 cites W2095624632 @default.
- W2078325900 cites W2096275407 @default.
- W2078325900 cites W2096400590 @default.
- W2078325900 cites W2101758948 @default.
- W2078325900 cites W2105083288 @default.
- W2078325900 cites W2110713840 @default.
- W2078325900 cites W2111893100 @default.
- W2078325900 cites W2119769441 @default.
- W2078325900 cites W2125008811 @default.
- W2078325900 cites W2125463311 @default.
- W2078325900 cites W2126700118 @default.
- W2078325900 cites W2131727615 @default.
- W2078325900 cites W21339481 @default.
- W2078325900 cites W2134133524 @default.
- W2078325900 cites W2134561621 @default.