FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078336460> ?p ?o ?g. }

• W2078336460 endingPage "18" @default.
• W2078336460 startingPage "11" @default.
• W2078336460 abstract "The study evaluates the clinical course and the development of systolic and diastolic left ventricular function in patients with chronic myocarditis with or without autoantibodies against cardiac myosin.Patients with myocarditis often show autoantibodies against cardiac myosin. The clinical and pathophysiologic significance of these antimyosin autoantibodies (AMAAB) is yet unknown. The results from studies comparing the clinical course and the development of left ventricular function in patients with chronic myocarditis with or without AMAAB are not yet available.Thirty-three patients with biopsy proven chronic myocarditis underwent analysis of AMAAB, right and left heart catheterization and left ventriculography at baseline and after six months. Left ventricular volumes and ejection fraction as well as the time constant of left ventricular relaxation tau and the constant of myocardial stiffness b were determined at baseline and at follow-up.In 17 (52%) patients, AMAAB could be detected at baseline. After six months, AMAAB were still found in 13 (76%) initially antibody-positive patients. No initially antibody-negative (n = 16) patient developed AMAAB during follow-up. Clinical symptoms improved slightly in antibody-negative patients and remained stable in antibody-positive patients. Left ventricular ejection fraction developed significantly better in antibody-negative patients (+8.9 +/- 10.1%) compared with antibody-positive patients (-0.1 +/- 9.4%) (p < 0.012). Stroke volume (SV) and stroke volume index (SVI) also improved in antibody-negative patients (SV: +20 +/- 31 ml; SVI: +10 +/- 17 ml) compared with antibody-positive patients (SV: -14 +/- 43 ml; SVI: -8 +/- 22 ml) (SV: p < 0.015; SVI: p < 0.016). Left ventricular end-diastolic and end-systolic volumes and the time constant of left ventricular relaxation tau did not change significantly different in antibody-positive and antibody-negative patients. The constant of myocardial stiffness b improved significantly in antibody-negative patients (-6.1 +/- 10.8) compared with antibody-positive patients (+7.3 +/- 22.6) (p < 0.040). Analyzing only the persistently antibody-positive patients yielded essentially the same results.Antimyosin autoantibodies are associated with worse development of left ventricular systolic function and diastolic stiffness in patients with chronic myocarditis." @default.
• W2078336460 created "2016-06-24" @default.
• W2078336460 creator A5001737123 @default.
• W2078336460 creator A5005923993 @default.
• W2078336460 creator A5028571409 @default.
• W2078336460 creator A5067743417 @default.
• W2078336460 creator A5074388153 @default.
• W2078336460 date "2000-01-01" @default.
• W2078336460 modified "2023-10-17" @default.
• W2078336460 title "Antimyosin autoantibodies are associated with deterioration of systolic and diastolic left ventricular function in patients with chronic myocarditis" @default.
• W2078336460 cites W1968564818 @default.
• W2078336460 cites W1970888273 @default.
• W2078336460 cites W1976768199 @default.
• W2078336460 cites W1976922801 @default.
• W2078336460 cites W1981925675 @default.
• W2078336460 cites W1984281014 @default.
• W2078336460 cites W1985296034 @default.
• W2078336460 cites W1993492475 @default.
• W2078336460 cites W1995259741 @default.
• W2078336460 cites W1995265994 @default.
• W2078336460 cites W2001184568 @default.
• W2078336460 cites W2013146587 @default.
• W2078336460 cites W2021940395 @default.
• W2078336460 cites W2023791632 @default.
• W2078336460 cites W2026531978 @default.
• W2078336460 cites W2031070919 @default.
• W2078336460 cites W2032724298 @default.
• W2078336460 cites W2036393178 @default.
• W2078336460 cites W2036456645 @default.
• W2078336460 cites W2038677584 @default.
• W2078336460 cites W2045704168 @default.
• W2078336460 cites W2045919227 @default.
• W2078336460 cites W2059290727 @default.
• W2078336460 cites W2062283925 @default.
• W2078336460 cites W2062402155 @default.
• W2078336460 cites W2063536010 @default.
• W2078336460 cites W2066283094 @default.
• W2078336460 cites W2066852687 @default.
• W2078336460 cites W2068081034 @default.
• W2078336460 cites W2082605100 @default.
• W2078336460 cites W2086280571 @default.
• W2078336460 cites W2092238277 @default.
• W2078336460 cites W2125914320 @default.
• W2078336460 cites W2130038458 @default.
• W2078336460 cites W2138524724 @default.
• W2078336460 cites W2145258710 @default.
• W2078336460 cites W2167075555 @default.
• W2078336460 cites W2167217753 @default.
• W2078336460 cites W259174617 @default.
• W2078336460 doi "https://doi.org/10.1016/s0735-1097(99)00485-4" @default.
• W2078336460 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10636253" @default.
• W2078336460 hasPublicationYear "2000" @default.
• W2078336460 type Work @default.
• W2078336460 sameAs 2078336460 @default.
• W2078336460 citedByCount "169" @default.
• W2078336460 countsByYear W20783364602012 @default.
• W2078336460 countsByYear W20783364602013 @default.
• W2078336460 countsByYear W20783364602014 @default.
• W2078336460 countsByYear W20783364602015 @default.
• W2078336460 countsByYear W20783364602016 @default.
• W2078336460 countsByYear W20783364602017 @default.
• W2078336460 countsByYear W20783364602018 @default.
• W2078336460 countsByYear W20783364602019 @default.
• W2078336460 countsByYear W20783364602020 @default.
• W2078336460 countsByYear W20783364602021 @default.
• W2078336460 countsByYear W20783364602022 @default.
• W2078336460 countsByYear W20783364602023 @default.
• W2078336460 crossrefType "journal-article" @default.
• W2078336460 hasAuthorship W2078336460A5001737123 @default.
• W2078336460 hasAuthorship W2078336460A5005923993 @default.
• W2078336460 hasAuthorship W2078336460A5028571409 @default.
• W2078336460 hasAuthorship W2078336460A5067743417 @default.
• W2078336460 hasAuthorship W2078336460A5074388153 @default.
• W2078336460 hasConcept C111566952 @default.
• W2078336460 hasConcept C126322002 @default.
• W2078336460 hasConcept C159654299 @default.
• W2078336460 hasConcept C163764329 @default.
• W2078336460 hasConcept C164705383 @default.
• W2078336460 hasConcept C203014093 @default.
• W2078336460 hasConcept C2777385415 @default.
• W2078336460 hasConcept C2778198053 @default.
• W2078336460 hasConcept C2780875844 @default.
• W2078336460 hasConcept C57900726 @default.
• W2078336460 hasConcept C71924100 @default.
• W2078336460 hasConcept C78085059 @default.
• W2078336460 hasConcept C80461066 @default.
• W2078336460 hasConcept C84393581 @default.
• W2078336460 hasConceptScore W2078336460C111566952 @default.
• W2078336460 hasConceptScore W2078336460C126322002 @default.
• W2078336460 hasConceptScore W2078336460C159654299 @default.
• W2078336460 hasConceptScore W2078336460C163764329 @default.
• W2078336460 hasConceptScore W2078336460C164705383 @default.
• W2078336460 hasConceptScore W2078336460C203014093 @default.
• W2078336460 hasConceptScore W2078336460C2777385415 @default.
• W2078336460 hasConceptScore W2078336460C2778198053 @default.
• W2078336460 hasConceptScore W2078336460C2780875844 @default.
• W2078336460 hasConceptScore W2078336460C57900726 @default.
• W2078336460 hasConceptScore W2078336460C71924100 @default.

• next