Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078348080> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2078348080 endingPage "270" @default.
- W2078348080 startingPage "265" @default.
- W2078348080 abstract "Fixed-dose combinations (FDCs) are one of the options for improving blood pressure (BP) goal attainment. We enrolled 141 patients and evaluated the efficacy and safety between a fixed dose of olmesartan/amlodipine (OA) and a double dose of amlodipine (DA) for treating mild to moderate hypertension after amlodipine monotherapy failure. After at least 2 weeks of monotherapy failure, the patients were randomized to receive either OA or DA for 8 weeks. We compared the systolic blood pressure (SBP)-lowering efficacy of the OA and DA using both an office BP and an ambulatory blood pressure monitoring (ABPM) device. The intent-to-treat analysis found that the early (2nd week) and final visit (8th week) SBP reductions were significantly greater in those patients receiving OA (n = 70) than DA (n = 71) (17.57 ± 15.49 vs. 10.46 ± 13.36 and 24.89 ± 14.09 vs. 17.03 ± 13.27 mmHg, p = 0.002 and 0.001, respectively). Among those using ABPM, the patients with 8-week OA had a greater SBP-lowering effect in comparison with those on DA (14.08 ± 10.74 vs. 6.32 ± 10.21, p = 0.018). Both treatment strategies were well tolerated. This study showed that an OA FDC is more effective than DA in reducing SBP for mild to moderate hypertension after the failure of amlodipine monotherapy." @default.
- W2078348080 created "2016-06-24" @default.
- W2078348080 creator A5009262253 @default.
- W2078348080 creator A5024523357 @default.
- W2078348080 creator A5025771453 @default.
- W2078348080 creator A5050229260 @default.
- W2078348080 creator A5050934844 @default.
- W2078348080 creator A5051813147 @default.
- W2078348080 creator A5082752193 @default.
- W2078348080 date "2012-12-21" @default.
- W2078348080 modified "2023-10-18" @default.
- W2078348080 title "Efficacy and tolerability between an olmesartan/amlodipine fixed-dose combination and an amlodipine double dose in mild to moderate hypertension" @default.
- W2078348080 cites W1994658812 @default.
- W2078348080 cites W2025309234 @default.
- W2078348080 cites W2029346078 @default.
- W2078348080 cites W2029897366 @default.
- W2078348080 cites W2046575388 @default.
- W2078348080 cites W2054528712 @default.
- W2078348080 cites W2061749460 @default.
- W2078348080 cites W2090024638 @default.
- W2078348080 cites W2110880027 @default.
- W2078348080 cites W2117060457 @default.
- W2078348080 cites W2141784797 @default.
- W2078348080 cites W2156121263 @default.
- W2078348080 cites W2168367179 @default.
- W2078348080 cites W2168407152 @default.
- W2078348080 cites W2303651371 @default.
- W2078348080 cites W4253582190 @default.
- W2078348080 doi "https://doi.org/10.1016/j.kjms.2012.09.005" @default.
- W2078348080 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23639513" @default.
- W2078348080 hasPublicationYear "2012" @default.
- W2078348080 type Work @default.
- W2078348080 sameAs 2078348080 @default.
- W2078348080 citedByCount "4" @default.
- W2078348080 countsByYear W20783480802016 @default.
- W2078348080 countsByYear W20783480802022 @default.
- W2078348080 crossrefType "journal-article" @default.
- W2078348080 hasAuthorship W2078348080A5009262253 @default.
- W2078348080 hasAuthorship W2078348080A5024523357 @default.
- W2078348080 hasAuthorship W2078348080A5025771453 @default.
- W2078348080 hasAuthorship W2078348080A5050229260 @default.
- W2078348080 hasAuthorship W2078348080A5050934844 @default.
- W2078348080 hasAuthorship W2078348080A5051813147 @default.
- W2078348080 hasAuthorship W2078348080A5082752193 @default.
- W2078348080 hasBestOaLocation W20783480801 @default.
- W2078348080 hasConcept C126322002 @default.
- W2078348080 hasConcept C126894567 @default.
- W2078348080 hasConcept C149323552 @default.
- W2078348080 hasConcept C164705383 @default.
- W2078348080 hasConcept C197934379 @default.
- W2078348080 hasConcept C2776623344 @default.
- W2078348080 hasConcept C2778375690 @default.
- W2078348080 hasConcept C2779646130 @default.
- W2078348080 hasConcept C2779766728 @default.
- W2078348080 hasConcept C71924100 @default.
- W2078348080 hasConcept C84393581 @default.
- W2078348080 hasConceptScore W2078348080C126322002 @default.
- W2078348080 hasConceptScore W2078348080C126894567 @default.
- W2078348080 hasConceptScore W2078348080C149323552 @default.
- W2078348080 hasConceptScore W2078348080C164705383 @default.
- W2078348080 hasConceptScore W2078348080C197934379 @default.
- W2078348080 hasConceptScore W2078348080C2776623344 @default.
- W2078348080 hasConceptScore W2078348080C2778375690 @default.
- W2078348080 hasConceptScore W2078348080C2779646130 @default.
- W2078348080 hasConceptScore W2078348080C2779766728 @default.
- W2078348080 hasConceptScore W2078348080C71924100 @default.
- W2078348080 hasConceptScore W2078348080C84393581 @default.
- W2078348080 hasIssue "5" @default.
- W2078348080 hasLocation W20783480801 @default.
- W2078348080 hasLocation W20783480802 @default.
- W2078348080 hasOpenAccess W2078348080 @default.
- W2078348080 hasPrimaryLocation W20783480801 @default.
- W2078348080 hasRelatedWork W2013678571 @default.
- W2078348080 hasRelatedWork W2044032603 @default.
- W2078348080 hasRelatedWork W2053932973 @default.
- W2078348080 hasRelatedWork W2055006209 @default.
- W2078348080 hasRelatedWork W2078348080 @default.
- W2078348080 hasRelatedWork W2092901492 @default.
- W2078348080 hasRelatedWork W2136645589 @default.
- W2078348080 hasRelatedWork W2549469951 @default.
- W2078348080 hasRelatedWork W2989847253 @default.
- W2078348080 hasRelatedWork W3028927003 @default.
- W2078348080 hasVolume "29" @default.
- W2078348080 isParatext "false" @default.
- W2078348080 isRetracted "false" @default.
- W2078348080 magId "2078348080" @default.
- W2078348080 workType "article" @default.