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• W2078351936 startingPage "154" @default.
• W2078351936 abstract "Psoriasis is a chronic inflammatory hyperproliferative disease of the skin, scalp, nails, and joints. The physical symptoms of psoriasis include itching, irritation, burning/stinging, sensitivity, and pain. Patients also suffer psychological distress, especially as a result of stigmatization, self-consciousness, and embarrassment, which can in turn affect employment and social activities. Relatively high rates of depression are reported in patients with psoriasis. Inflammatory cytokines such as tumor necrosis factor alpha, interferon gamma, and other type 1 cytokines play an important role in the pathogenesis and comorbidities of psoriasis. Data from both animal and human studies suggest that these cytokines are linked to depression. Some psoriasis treatments have demonstrated improvements in symptoms of psoriasis as well as in measures of depression and health-related quality of life. Physicians managing patients with psoriasis must be aware of the psychological effects of psoriasis and need to use a multifaceted approach to managing this disease, focusing on both the physical and psychological aspects." @default.
• W2078351936 created "2016-06-24" @default.
• W2078351936 creator A5003115771 @default.
• W2078351936 creator A5031855679 @default.
• W2078351936 date "2009-07-01" @default.
• W2078351936 modified "2023-09-27" @default.
• W2078351936 title "Depression and Quality of Life in Psoriasis" @default.
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• W2078351936 doi "https://doi.org/10.3810/pgm.2009.07.2040" @default.
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