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• W2078361288 startingPage "1" @default.
• W2078361288 abstract "BAFF is a potent B-cell survival factor, and it plays an essential role in B-cell homeostasis and B-cell function in the periphery. Both normal and autoreactive B cells are BAFF dependent; however, excess BAFF promotes the survival, growth, and maturation of autoreactive B cells. When overexpressed, BAFF protects B cells from apoptosis, thereby contributing to autoimmunity. Three independent studies have shown higher BAFF levels in the circulation of MG patients. BAFF may play an important role in the pathogenesis of MG. BAFF antagonists may well provide new treatment options for MG patients, particularly those patients with thymic lymphoid follicular hyperplasia." @default.
• W2078361288 created "2016-06-24" @default.
• W2078361288 creator A5009994219 @default.
• W2078361288 creator A5091084513 @default.
• W2078361288 date "2011-01-01" @default.
• W2078361288 modified "2023-09-30" @default.
• W2078361288 title "B-Cell-Activating Factor and Autoimmune Myasthenia Gravis" @default.
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