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- W2078363418 abstract "Results Group of patients exposed to ASA preoperatively had lower values of ASPI test (P<0.001) comparing to patients not receiving ASA. However, we registered 28.6% ASA resistant patients. Both ASPI (P<0.001) and ADP (P<0.001) test values increased significantly at POD 4, suggesting postoperative platelet hyperactivity. Postoperatively, we registered 33.3% ASA resistant patients despite higher ASA dosing regimen. Conclusion MEA can recognize patients with ASA resistance during the both the pre- and post- CABG period. Postoperatively, ASA 300mg did not sufficiently inhibit platelet aggregation in 33.3% patients. In this subgroup, dual antiplatelet therapy with ASA and clopidogrel could be useful for maintaining graft patency, and preventing adverse ischemic events." @default.
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- W2078363418 date "2013-09-01" @default.
- W2078363418 modified "2023-10-12" @default.
- W2078363418 title "Impact of antiplatelet therapy and cardiopulmonary bypass on platelet function in patients undergoing coronary artery bypass grafting using multiple electrode aggregometry" @default.
- W2078363418 doi "https://doi.org/10.1186/1749-8090-8-s1-p63" @default.
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