FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078373882> ?p ?o ?g. }

• W2078373882 endingPage "11" @default.
• W2078373882 startingPage "5" @default.
• W2078373882 abstract "Fibrin sealants are used in a wide range of surgeries, primarily as hemostatic agents, but also to assist tissue sealing and wound healing. While all fibrin sealants contain fibrinogen and thrombin, they differ in their final composition. This affects the properties of the resulting fibrin clot and may influence their use in different surgical procedures. Sealants with high concentrations of fibrinogen tend to produce stronger clots, whereas those containing higher concentrations of thrombin form clots rapidly. This is essential when rapid hemostasis is required to stop blood loss (e.g. suturing of blood vessels). However, in situations that require careful adjustment of tissue (e.g. a skin flap) a slower clot formation is advantageous. Some sealants are supplemented with factor XIII and this may increase the tensile strength and stability of the clot and improve hemostasis. Antifibrinolytic agents (e.g. aprotinin and aminocaproic acid) increase the lifespan of the clot by inhibiting fibrinolysis. Fibrin sealants containing aprotinin may have an added advantage when used on surgical sites with naturally high concentrations of fibrinolytic agents. The physical properties of the fibrin sealants also vary. For example, the fibrinogen component is relatively viscous and requires a lot of force to inject it through a long catheter. Fibrin sealants with a fibrinogen component of low viscosity are easier to use than highly viscous solutions in surgical situations where the sealant is applied by a catheter. Until recently, the use of fibrin sealants in the USA has been limited to noncommercial products — ‘home-brews’. The fibrinogen concentration of these products can vary between preparations, with subsequent variation in the mechanical strength of the clot making handling difficult. The introduction of commercial sealants into the USA with consistent composition should reduce the varying performance of fibrin sealants, although autologous and point-of-use prepared sealants may still vary. Consistency of performance is expected to result in an increased use of fibrin sealants both in established and novel fields of surgery." @default.
• W2078373882 created "2016-06-24" @default.
• W2078373882 creator A5004625882 @default.
• W2078373882 date "2003-08-01" @default.
• W2078373882 modified "2023-10-10" @default.
• W2078373882 title "Fibrin sealants in clinical practice" @default.
• W2078373882 cites W1543599519 @default.
• W2078373882 cites W1722477279 @default.
• W2078373882 cites W172524543 @default.
• W2078373882 cites W1884871635 @default.
• W2078373882 cites W1964811218 @default.
• W2078373882 cites W1972978973 @default.
• W2078373882 cites W1978160662 @default.
• W2078373882 cites W1999033948 @default.
• W2078373882 cites W1999639128 @default.
• W2078373882 cites W2019617760 @default.
• W2078373882 cites W2022685238 @default.
• W2078373882 cites W2023628867 @default.
• W2078373882 cites W2026665730 @default.
• W2078373882 cites W2041535925 @default.
• W2078373882 cites W2048530003 @default.
• W2078373882 cites W2058517444 @default.
• W2078373882 cites W2065894144 @default.
• W2078373882 cites W2075946772 @default.
• W2078373882 cites W2080469312 @default.
• W2078373882 cites W2081645706 @default.
• W2078373882 cites W2082172508 @default.
• W2078373882 cites W2082182787 @default.
• W2078373882 cites W2088048448 @default.
• W2078373882 cites W2088294135 @default.
• W2078373882 cites W2089344564 @default.
• W2078373882 cites W2092160826 @default.
• W2078373882 cites W2103258742 @default.
• W2078373882 cites W2104605781 @default.
• W2078373882 cites W2109271915 @default.
• W2078373882 cites W2114659602 @default.
• W2078373882 cites W2131209428 @default.
• W2078373882 cites W2136384394 @default.
• W2078373882 cites W2141819286 @default.
• W2078373882 cites W2147407797 @default.
• W2078373882 cites W2150668928 @default.
• W2078373882 cites W2409946829 @default.
• W2078373882 cites W2412730952 @default.
• W2078373882 cites W2416434098 @default.
• W2078373882 cites W2471970900 @default.
• W2078373882 cites W3043280949 @default.
• W2078373882 cites W77663427 @default.
• W2078373882 cites W2472780893 @default.
• W2078373882 doi "https://doi.org/10.1016/s0967-2109(03)00065-6" @default.
• W2078373882 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12869982" @default.
• W2078373882 hasPublicationYear "2003" @default.
• W2078373882 type Work @default.
• W2078373882 sameAs 2078373882 @default.
• W2078373882 citedByCount "105" @default.
• W2078373882 countsByYear W20783738822012 @default.
• W2078373882 countsByYear W20783738822013 @default.
• W2078373882 countsByYear W20783738822014 @default.
• W2078373882 countsByYear W20783738822015 @default.
• W2078373882 countsByYear W20783738822016 @default.
• W2078373882 countsByYear W20783738822017 @default.
• W2078373882 countsByYear W20783738822018 @default.
• W2078373882 countsByYear W20783738822019 @default.
• W2078373882 countsByYear W20783738822020 @default.
• W2078373882 countsByYear W20783738822021 @default.
• W2078373882 countsByYear W20783738822022 @default.
• W2078373882 countsByYear W20783738822023 @default.
• W2078373882 crossrefType "journal-article" @default.
• W2078373882 hasAuthorship W2078373882A5004625882 @default.
• W2078373882 hasConcept C126322002 @default.
• W2078373882 hasConcept C136229726 @default.
• W2078373882 hasConcept C141071460 @default.
• W2078373882 hasConcept C178790620 @default.
• W2078373882 hasConcept C181199279 @default.
• W2078373882 hasConcept C185592680 @default.
• W2078373882 hasConcept C203014093 @default.
• W2078373882 hasConcept C2775883587 @default.
• W2078373882 hasConcept C2776825266 @default.
• W2078373882 hasConcept C2777292125 @default.
• W2078373882 hasConcept C2778589496 @default.
• W2078373882 hasConcept C2779036427 @default.
• W2078373882 hasConcept C2779637338 @default.
• W2078373882 hasConcept C2779672106 @default.
• W2078373882 hasConcept C2780269544 @default.
• W2078373882 hasConcept C2780799893 @default.
• W2078373882 hasConcept C2781071845 @default.
• W2078373882 hasConcept C2781436528 @default.
• W2078373882 hasConcept C2991743468 @default.
• W2078373882 hasConcept C54173615 @default.
• W2078373882 hasConcept C55493867 @default.
• W2078373882 hasConcept C71924100 @default.
• W2078373882 hasConcept C89560881 @default.
• W2078373882 hasConceptScore W2078373882C126322002 @default.
• W2078373882 hasConceptScore W2078373882C136229726 @default.
• W2078373882 hasConceptScore W2078373882C141071460 @default.
• W2078373882 hasConceptScore W2078373882C178790620 @default.
• W2078373882 hasConceptScore W2078373882C181199279 @default.
• W2078373882 hasConceptScore W2078373882C185592680 @default.
• W2078373882 hasConceptScore W2078373882C203014093 @default.

• next