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• W2078378639 abstract "Acute pancreatitis (AP) is a rare but life-threatening complication of SLE. The current study evaluated the clinical characteristics and risk factors for the mortality of patients with SLE-related AP in a cohort of South China. Methods . Inpatient medical records of SLE-related AP were retrospectively reviewed. Results . 27 out of 4053 SLE patients were diagnosed as SLE-related AP, with an overall prevalence of 0.67%, annual incidence of 0.56‰ and mortality of 37.04%. SLE patients with AP presented with higher SLEDAI score (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mn>21.70</mml:mn><mml:mo>±</mml:mo><mml:mn>10.32</mml:mn></mml:math>versus<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mn>16.17</mml:mn><mml:mo>±</mml:mo><mml:mn>7.51</mml:mn></mml:math>,<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.03</mml:mn></mml:math>), more organ systems involvement (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mn>5.70</mml:mn><mml:mo>±</mml:mo><mml:mn>1.56</mml:mn></mml:math>versus<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mn>3.96</mml:mn><mml:mo>±</mml:mo><mml:mn>1.15</mml:mn></mml:math>,<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.001</mml:mn></mml:math>), and higher mortality (37.04% versus 0,<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.001</mml:mn></mml:math>), compared to patients without AP. Severe AP (SAP) patients had a significant higher mortality rate compared to mild AP (MAP) (75% versus 21.05%,<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.014</mml:mn></mml:math>). 16 SLE-related AP patients received intensive GC treatment, 75% of them exhibited favorable prognosis. Conclusion . SLE-related AP is rare but concomitant with high mortality in South Chinese people, especially in those SAP patients. Activity of SLE, multiple-organ systems involvement may attribute to the severity and mortality of AP. Appropriate glucocorticosteroid (GC) treatment leads to better prognosis in majority of SLE patients with AP." @default.
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• W2078378639 date "2012-01-01" @default.
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• W2078378639 title "Systemic-Lupus-Erythematosus-Related Acute Pancreatitis: A Cohort from South China" @default.
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• W2078378639 doi "https://doi.org/10.1155/2012/568564" @default.
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