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- W2078412591 abstract "Abstract The administration of the ionophore A23187 to superfused rat adrenal cortical tissue slices resulted in a significant elevation in corticosterone production. Removal of calcium from the superfusion medium prevented this ionophore induced corticosteroidogenesis. Threshold amounts of ionophore potentiated the steroidogenic action of 1 mU but not 10 mU ACTH under in vitro conditions. This potentiation by ionophore on ACTH stimulated steroid production was not observed when calcium was omitted from the superfusing medium. Potentiation by the ionophore on dbCAMP or CAMP stimulated steroid formation was not observed for any dose of cyclic nucleotide employed." @default.
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- W2078412591 date "1978-09-01" @default.
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- W2078412591 title "Effects of ionophore A23187 on in vitro rat adrenal corticosterone production" @default.
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- W2078412591 doi "https://doi.org/10.1016/0024-3205(78)90354-5" @default.
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