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- W2078421915 abstract "The isolated single electroplax was mounted between two pools of fluid, one initially non-radioactive, the other containing 14 C choline. Treated cells were exposed for 20 min to 1 mg per ml concentrations of various enzymes and venoms. Cottonmouth moccasin venom (CMV) caused a hundred-fold increase in the control level (∼0.01 per cent per 10 min) of penetration. Acid-boiled CMV, phospholipase C and lipase caused only a 2- to 3-fold increase in penetration while the following treatments had no effect on permeability: alkaline-boiled CMV, phospholipase D, hyaluronidase, chymotrypsin, trypsin, venom 1-amino acid oxidase and phosphodiesterase, purified cobra neurotoxin (0.2 mg/ml), cetyltrimethylammonium bromide, Centruroides sculpturatus , Notechis scutatus , Heloderma horridum and Naja naja venoms. The action of acid-boiled CMV is associated with extensive phospholipid splitting, therefore, it does not appear that intact phospholipids are necessary for membrane permeability. The component of unboiled CMV which increases permeability is not known." @default.
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- W2078421915 date "1973-02-01" @default.
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- W2078421915 title "Venoms and enzymes: effects on permeability of isolated single electroplax" @default.
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- W2078421915 doi "https://doi.org/10.1016/0041-0101(73)90076-7" @default.
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