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• W2078432812 abstract "Five lactose-inhibitable lectins have been isolated from snake venoms. These five share certain biochemical properties but are not identical (Gartner, Stocker & Williams, 1980; Gartner & Ogilvie, 1984). In this study the lectins were tested for their ability to stimulate lymphocytes to undergo DNA synthesis. We found that three of the lectins were comparable in mitogenic activity to the T cell lectin, concanavalin A (Con A). The mitogenic activity was blocked by lactose, a sugar which also blocks the haemagglutination activity of these lectins. Although mitogenic response appeared to be due to T cells, it depended on the presence of accessory cells in the culture. This requirement for macrophages could be replaced by the phorbol ester tumour promoter, 12-o-tetradecanoylphorbol-13-acetate (TPA)." @default.
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• W2078432812 date "1986-09-01" @default.
• W2078432812 modified "2023-09-25" @default.
• W2078432812 title "Mitogenic Activity of Snake Venom Lectins" @default.
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• W2078432812 doi "https://doi.org/10.1111/j.1365-2184.1986.tb00756.x" @default.
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