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- W2078441105 abstract "The binding of cytotoxic T lymphocytes to target cells was studied by ultrastructural and tracer techniques. It was found that binding was achieved through interaction of the microvilli of both cells and that only a relatively small proportion of the cell surface was involved. Short points of contact, averaging 1500 Å in length, were the main form of junction. Periodic substructures were observed in some of the contact points. The transfer of cytoplasmic content from effector to target cell and vice versa was investigated, but no fluorescein or 51Cr-labeled components were transferred during the interaction. Examination of cell organelle localization during the interaction revealed that microfilaments were the only cellular components which localized at the contact area; the well-developed Golgi apparatus of the cytotoxic lymphocytes was randomly distributed." @default.
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- W2078441105 date "1976-07-01" @default.
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- W2078441105 title "Contact regions of cytotoxic T lymphocyte-target cell conjugates" @default.
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- W2078441105 doi "https://doi.org/10.1016/0008-8749(76)90095-2" @default.
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