FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078441750> ?p ?o ?g. }

• W2078441750 abstract "We have examined the physiological properties of transmission at newly formed synapses between sympathetic preganglionic neurons and sympathetic ganglion neurons in vitro. Chick neurons were labeled with fluorescent carbocyanine dyes before they were placed into culture (Honig and Hume, 1986), and were studied by making intracellular recordings during the first 2 weeks of coculture. Evoked monosynaptic excitatory postsynaptic potentials (EPSPs) were not observed until 48 h of coculture. Beyond this time, the frequency with which connected pairs could be found did not vary greatly with time. With repetitive stimulation, the evoked monosynaptic EPSPs fluctuated in amplitude from trial to trial and showed depression at frequencies as low as 1 Hz. To gain further information about the quantitative properties of transmission at newly formed synapses, we analyzed the pattern of fluctuations of delayed release EPSPs. In mature systems, delayed release EPSPs are known to represent responses to single quanta, or to the synchronous release of a small number of quanta. For more than half of the connections we studied, the histograms of delayed release EPSPs were extremely broad. This result suggested that either quantal responses are drawn from a continuous distribution that has a large coefficient of variation or that there are several distinct size classes of quantal responses. The pattern of fluctuations of monosynaptic EPSPs was consistent with both of these possibilities, and was inconsistent with the possibility that monosynaptic EPSPs are composed of quantal subunits with very little intrinsic variation. Although variation in the size of responses to single quanta might arise in a number of ways, one attractive explanation for our results is that the density and type of acetylcholine receptors varies among the different synaptic sites on the surface of developing sympathetic ganglion neurons." @default.
• W2078441750 created "2016-06-24" @default.
• W2078441750 creator A5017035439 @default.
• W2078441750 creator A5031863637 @default.
• W2078441750 date "1991-04-01" @default.
• W2078441750 modified "2023-09-26" @default.
• W2078441750 title "Physiological properties of newly formed synapses between sympathetic preganglionic neurons and sympathetic ganglion neurons" @default.
• W2078441750 cites W1595148250 @default.
• W2078441750 cites W1749635502 @default.
• W2078441750 cites W1973506409 @default.
• W2078441750 cites W1978520477 @default.
• W2078441750 cites W1982469517 @default.
• W2078441750 cites W1993516404 @default.
• W2078441750 cites W2003974913 @default.
• W2078441750 cites W2007001696 @default.
• W2078441750 cites W2012521653 @default.
• W2078441750 cites W2016102536 @default.
• W2078441750 cites W2017694881 @default.
• W2078441750 cites W2019163178 @default.
• W2078441750 cites W2030601402 @default.
• W2078441750 cites W2033548549 @default.
• W2078441750 cites W2038346963 @default.
• W2078441750 cites W2039871661 @default.
• W2078441750 cites W2044838769 @default.
• W2078441750 cites W2051805011 @default.
• W2078441750 cites W2055334158 @default.
• W2078441750 cites W2065757451 @default.
• W2078441750 cites W2067773093 @default.
• W2078441750 cites W2067995523 @default.
• W2078441750 cites W2068380790 @default.
• W2078441750 cites W2068435529 @default.
• W2078441750 cites W2069362932 @default.
• W2078441750 cites W2075920660 @default.
• W2078441750 cites W2090015428 @default.
• W2078441750 cites W2106081526 @default.
• W2078441750 cites W2107517936 @default.
• W2078441750 cites W2118946849 @default.
• W2078441750 cites W2130795310 @default.
• W2078441750 cites W2134343364 @default.
• W2078441750 cites W2169842162 @default.
• W2078441750 cites W2338790955 @default.
• W2078441750 doi "https://doi.org/10.1002/neu.480220305" @default.
• W2078441750 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1653822" @default.
• W2078441750 hasPublicationYear "1991" @default.
• W2078441750 type Work @default.
• W2078441750 sameAs 2078441750 @default.
• W2078441750 citedByCount "6" @default.
• W2078441750 crossrefType "journal-article" @default.
• W2078441750 hasAuthorship W2078441750A5017035439 @default.
• W2078441750 hasAuthorship W2078441750A5031863637 @default.
• W2078441750 hasBestOaLocation W20784417502 @default.
• W2078441750 hasConcept C112592302 @default.
• W2078441750 hasConcept C169760540 @default.
• W2078441750 hasConcept C170493617 @default.
• W2078441750 hasConcept C17077164 @default.
• W2078441750 hasConcept C197341189 @default.
• W2078441750 hasConcept C200170125 @default.
• W2078441750 hasConcept C24998067 @default.
• W2078441750 hasConcept C2777646271 @default.
• W2078441750 hasConcept C55493867 @default.
• W2078441750 hasConcept C86803240 @default.
• W2078441750 hasConceptScore W2078441750C112592302 @default.
• W2078441750 hasConceptScore W2078441750C169760540 @default.
• W2078441750 hasConceptScore W2078441750C170493617 @default.
• W2078441750 hasConceptScore W2078441750C17077164 @default.
• W2078441750 hasConceptScore W2078441750C197341189 @default.
• W2078441750 hasConceptScore W2078441750C200170125 @default.
• W2078441750 hasConceptScore W2078441750C24998067 @default.
• W2078441750 hasConceptScore W2078441750C2777646271 @default.
• W2078441750 hasConceptScore W2078441750C55493867 @default.
• W2078441750 hasConceptScore W2078441750C86803240 @default.
• W2078441750 hasLocation W20784417501 @default.
• W2078441750 hasLocation W20784417502 @default.
• W2078441750 hasLocation W20784417503 @default.
• W2078441750 hasLocation W20784417504 @default.
• W2078441750 hasOpenAccess W2078441750 @default.
• W2078441750 hasPrimaryLocation W20784417501 @default.
• W2078441750 hasRelatedWork W1643544035 @default.
• W2078441750 hasRelatedWork W2039958681 @default.
• W2078441750 hasRelatedWork W2064685631 @default.
• W2078441750 hasRelatedWork W2070493184 @default.
• W2078441750 hasRelatedWork W2081857442 @default.
• W2078441750 hasRelatedWork W2128819852 @default.
• W2078441750 hasRelatedWork W2137331977 @default.
• W2078441750 hasRelatedWork W2141954297 @default.
• W2078441750 hasRelatedWork W2752743978 @default.
• W2078441750 hasRelatedWork W2783611170 @default.
• W2078441750 isParatext "false" @default.
• W2078441750 isRetracted "false" @default.
• W2078441750 magId "2078441750" @default.
• W2078441750 workType "article" @default.