FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078443060> ?p ?o ?g. }

• W2078443060 abstract "The Epstein-Barr virus (EBV) infects more than 90% of the human population, and causes glandular fever as well as several more serious diseases. It is a tumor virus, and has been widely studied as a model system for cell transformation in humans. A central feature of the EBV life cycle is its ability to persist in human B cells in different latency states, denoted latency I, II, and III. In latency III the host cell is driven to cell proliferation and hence expansion of the viral population without entering the lytic pathway, while the latency I state is almost completely dormant. We here study the effective cooperativity of the viral C promoter, active in latency III EBV cell lines. We show that the unusually large number of binding sites of two competing transcription factors, one viral and one from the host, serves to make the switch sharper (higher Hill coefficient), either by cooperative binding between molecules of the same species when they bind, or by competition between the two species if there is sufficient steric hindrance." @default.
• W2078443060 created "2016-06-24" @default.
• W2078443060 creator A5047019776 @default.
• W2078443060 creator A5061076198 @default.
• W2078443060 creator A5066822010 @default.
• W2078443060 date "2007-12-18" @default.
• W2078443060 modified "2023-10-02" @default.
• W2078443060 title "Cooperative action in eukaryotic gene regulation: Physical properties of a viral example" @default.
• W2078443060 cites W1487461106 @default.
• W2078443060 cites W1578954095 @default.
• W2078443060 cites W1593308984 @default.
• W2078443060 cites W1594478849 @default.
• W2078443060 cites W1874041651 @default.
• W2078443060 cites W1930835920 @default.
• W2078443060 cites W1974090488 @default.
• W2078443060 cites W1995145440 @default.
• W2078443060 cites W2004920405 @default.
• W2078443060 cites W2014667800 @default.
• W2078443060 cites W2022891974 @default.
• W2078443060 cites W2034220289 @default.
• W2078443060 cites W2042583382 @default.
• W2078443060 cites W2046355391 @default.
• W2078443060 cites W2070531819 @default.
• W2078443060 cites W2086634897 @default.
• W2078443060 cites W2096591944 @default.
• W2078443060 cites W2127536294 @default.
• W2078443060 cites W2144347639 @default.
• W2078443060 cites W2146935052 @default.
• W2078443060 cites W2159040707 @default.
• W2078443060 cites W2163642716 @default.
• W2078443060 cites W4300439579 @default.
• W2078443060 cites W8014543 @default.
• W2078443060 doi "https://doi.org/10.1103/physreve.76.061909" @default.
• W2078443060 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18233871" @default.
• W2078443060 hasPublicationYear "2007" @default.
• W2078443060 type Work @default.
• W2078443060 sameAs 2078443060 @default.
• W2078443060 citedByCount "8" @default.
• W2078443060 countsByYear W20784430602012 @default.
• W2078443060 countsByYear W20784430602015 @default.
• W2078443060 countsByYear W20784430602019 @default.
• W2078443060 countsByYear W20784430602020 @default.
• W2078443060 countsByYear W20784430602022 @default.
• W2078443060 crossrefType "journal-article" @default.
• W2078443060 hasAuthorship W2078443060A5047019776 @default.
• W2078443060 hasAuthorship W2078443060A5061076198 @default.
• W2078443060 hasAuthorship W2078443060A5066822010 @default.
• W2078443060 hasBestOaLocation W20784430602 @default.
• W2078443060 hasConcept C104317684 @default.
• W2078443060 hasConcept C119599485 @default.
• W2078443060 hasConcept C127413603 @default.
• W2078443060 hasConcept C138885662 @default.
• W2078443060 hasConcept C140704245 @default.
• W2078443060 hasConcept C1491633281 @default.
• W2078443060 hasConcept C159047783 @default.
• W2078443060 hasConcept C166014724 @default.
• W2078443060 hasConcept C179926584 @default.
• W2078443060 hasConcept C182615771 @default.
• W2078443060 hasConcept C2522874641 @default.
• W2078443060 hasConcept C25897203 @default.
• W2078443060 hasConcept C2778852064 @default.
• W2078443060 hasConcept C2908647359 @default.
• W2078443060 hasConcept C41895202 @default.
• W2078443060 hasConcept C54355233 @default.
• W2078443060 hasConcept C71924100 @default.
• W2078443060 hasConcept C82876162 @default.
• W2078443060 hasConcept C86803240 @default.
• W2078443060 hasConcept C95444343 @default.
• W2078443060 hasConcept C99454951 @default.
• W2078443060 hasConceptScore W2078443060C104317684 @default.
• W2078443060 hasConceptScore W2078443060C119599485 @default.
• W2078443060 hasConceptScore W2078443060C127413603 @default.
• W2078443060 hasConceptScore W2078443060C138885662 @default.
• W2078443060 hasConceptScore W2078443060C140704245 @default.
• W2078443060 hasConceptScore W2078443060C1491633281 @default.
• W2078443060 hasConceptScore W2078443060C159047783 @default.
• W2078443060 hasConceptScore W2078443060C166014724 @default.
• W2078443060 hasConceptScore W2078443060C179926584 @default.
• W2078443060 hasConceptScore W2078443060C182615771 @default.
• W2078443060 hasConceptScore W2078443060C2522874641 @default.
• W2078443060 hasConceptScore W2078443060C25897203 @default.
• W2078443060 hasConceptScore W2078443060C2778852064 @default.
• W2078443060 hasConceptScore W2078443060C2908647359 @default.
• W2078443060 hasConceptScore W2078443060C41895202 @default.
• W2078443060 hasConceptScore W2078443060C54355233 @default.
• W2078443060 hasConceptScore W2078443060C71924100 @default.
• W2078443060 hasConceptScore W2078443060C82876162 @default.
• W2078443060 hasConceptScore W2078443060C86803240 @default.
• W2078443060 hasConceptScore W2078443060C95444343 @default.
• W2078443060 hasConceptScore W2078443060C99454951 @default.
• W2078443060 hasIssue "6" @default.
• W2078443060 hasLocation W20784430601 @default.
• W2078443060 hasLocation W20784430602 @default.
• W2078443060 hasLocation W20784430603 @default.
• W2078443060 hasOpenAccess W2078443060 @default.
• W2078443060 hasPrimaryLocation W20784430601 @default.
• W2078443060 hasRelatedWork W1487857142 @default.
• W2078443060 hasRelatedWork W201248837 @default.
• W2078443060 hasRelatedWork W2018457864 @default.
• W2078443060 hasRelatedWork W2034651939 @default.

• next