Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078463013> ?p ?o ?g. }
- W2078463013 endingPage "1648" @default.
- W2078463013 startingPage "1644" @default.
- W2078463013 abstract "This article presents a new, highly sensitive method for the identification of single nucleotide polymorphisms (SNPs) in homogeneous solutions using fluorescently labeled hairpin‐structured oligonucleotides (smart probes) and fluorescence single‐molecule spectroscopy. While the hairpin probe is closed, fluorescence intensity is quenched due to close contact between the chromophore and several guanosine residues. Upon hybridization to the respective target SNP sequence, contact is lost and the fluorescence intensity increases significantly. High specificity is achieved by blocking sequences containing mismatch with unlabeled oligonucleotides. Time‐resolved single‐molecule fluorescence spectroscopy enables the detection of individual smart probes passing a small detection volume. This method leads to a subnanomolar sensitivity for this single nucleotide specific DNA assay technique." @default.
- W2078463013 created "2016-06-24" @default.
- W2078463013 creator A5017815858 @default.
- W2078463013 creator A5069561322 @default.
- W2078463013 creator A5072082150 @default.
- W2078463013 creator A5087020799 @default.
- W2078463013 date "2007-03-20" @default.
- W2078463013 modified "2023-10-13" @default.
- W2078463013 title "DNA-probes for the highly sensitive identification of single nucleotide polymorphism using single-molecule spectroscopy" @default.
- W2078463013 cites W1631110814 @default.
- W2078463013 cites W1974909861 @default.
- W2078463013 cites W1982473418 @default.
- W2078463013 cites W1987739795 @default.
- W2078463013 cites W2011791206 @default.
- W2078463013 cites W2021116729 @default.
- W2078463013 cites W2026710381 @default.
- W2078463013 cites W2036620462 @default.
- W2078463013 cites W2065895057 @default.
- W2078463013 cites W2070721758 @default.
- W2078463013 cites W2073351293 @default.
- W2078463013 cites W2081927185 @default.
- W2078463013 cites W2082764409 @default.
- W2078463013 cites W2089951492 @default.
- W2078463013 cites W2108801883 @default.
- W2078463013 cites W2109122447 @default.
- W2078463013 cites W2120773494 @default.
- W2078463013 cites W2150648113 @default.
- W2078463013 cites W2159266386 @default.
- W2078463013 cites W2164375473 @default.
- W2078463013 doi "https://doi.org/10.1016/j.febslet.2007.03.031" @default.
- W2078463013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17399707" @default.
- W2078463013 hasPublicationYear "2007" @default.
- W2078463013 type Work @default.
- W2078463013 sameAs 2078463013 @default.
- W2078463013 citedByCount "22" @default.
- W2078463013 countsByYear W20784630132012 @default.
- W2078463013 countsByYear W20784630132013 @default.
- W2078463013 countsByYear W20784630132016 @default.
- W2078463013 countsByYear W20784630132019 @default.
- W2078463013 countsByYear W20784630132020 @default.
- W2078463013 countsByYear W20784630132022 @default.
- W2078463013 crossrefType "journal-article" @default.
- W2078463013 hasAuthorship W2078463013A5017815858 @default.
- W2078463013 hasAuthorship W2078463013A5069561322 @default.
- W2078463013 hasAuthorship W2078463013A5072082150 @default.
- W2078463013 hasAuthorship W2078463013A5087020799 @default.
- W2078463013 hasBestOaLocation W20784630131 @default.
- W2078463013 hasConcept C104317684 @default.
- W2078463013 hasConcept C111824103 @default.
- W2078463013 hasConcept C121332964 @default.
- W2078463013 hasConcept C12554922 @default.
- W2078463013 hasConcept C129312508 @default.
- W2078463013 hasConcept C130197536 @default.
- W2078463013 hasConcept C135763542 @default.
- W2078463013 hasConcept C144618238 @default.
- W2078463013 hasConcept C153209595 @default.
- W2078463013 hasConcept C158711907 @default.
- W2078463013 hasConcept C178790620 @default.
- W2078463013 hasConcept C185592680 @default.
- W2078463013 hasConcept C199191878 @default.
- W2078463013 hasConcept C2777995097 @default.
- W2078463013 hasConcept C32891209 @default.
- W2078463013 hasConcept C32909587 @default.
- W2078463013 hasConcept C512185932 @default.
- W2078463013 hasConcept C552990157 @default.
- W2078463013 hasConcept C55493867 @default.
- W2078463013 hasConcept C62520636 @default.
- W2078463013 hasConcept C86803240 @default.
- W2078463013 hasConcept C91881484 @default.
- W2078463013 hasConceptScore W2078463013C104317684 @default.
- W2078463013 hasConceptScore W2078463013C111824103 @default.
- W2078463013 hasConceptScore W2078463013C121332964 @default.
- W2078463013 hasConceptScore W2078463013C12554922 @default.
- W2078463013 hasConceptScore W2078463013C129312508 @default.
- W2078463013 hasConceptScore W2078463013C130197536 @default.
- W2078463013 hasConceptScore W2078463013C135763542 @default.
- W2078463013 hasConceptScore W2078463013C144618238 @default.
- W2078463013 hasConceptScore W2078463013C153209595 @default.
- W2078463013 hasConceptScore W2078463013C158711907 @default.
- W2078463013 hasConceptScore W2078463013C178790620 @default.
- W2078463013 hasConceptScore W2078463013C185592680 @default.
- W2078463013 hasConceptScore W2078463013C199191878 @default.
- W2078463013 hasConceptScore W2078463013C2777995097 @default.
- W2078463013 hasConceptScore W2078463013C32891209 @default.
- W2078463013 hasConceptScore W2078463013C32909587 @default.
- W2078463013 hasConceptScore W2078463013C512185932 @default.
- W2078463013 hasConceptScore W2078463013C552990157 @default.
- W2078463013 hasConceptScore W2078463013C55493867 @default.
- W2078463013 hasConceptScore W2078463013C62520636 @default.
- W2078463013 hasConceptScore W2078463013C86803240 @default.
- W2078463013 hasConceptScore W2078463013C91881484 @default.
- W2078463013 hasIssue "8" @default.
- W2078463013 hasLocation W20784630131 @default.
- W2078463013 hasLocation W20784630132 @default.
- W2078463013 hasOpenAccess W2078463013 @default.
- W2078463013 hasPrimaryLocation W20784630131 @default.
- W2078463013 hasRelatedWork W2068045552 @default.
- W2078463013 hasRelatedWork W2131630815 @default.