Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078472336> ?p ?o ?g. }
- W2078472336 abstract "To characterize HIV-1 genotypes in candidate populations for a prime-boost phase III vaccine trial in Thailand, specimens from prevalent and incident HIV-1 infections from a family planning clinic population in Rayong Province and a community cohort in Chon Buri Province, collected from 1998 to 2001, were genotyped. A new multiregion hybridization assay, MHAbce, capable of distinguishing HIV-1 CRF01_AE, subtype B, and subtype C and their recombinants, was developed and applied to prevalent infections. Most incident and selected prevalent infections were studied by complete genome sequencing. By MHAbce, 168 of 194 prevalent infections were genotyped. Of these, 90.5% were CRF01_AE, 2.4% were subtype B, and 7.2% showed discordant or dual probe reactivity, indicative of recombination or dual infection, respectively. Among 23 incident infections, 20 were sequenced. Eighteen CRF01_AE, one subtype B, and one CRF01/B recombinant strains were seen. Two CRF01/B and one CRF01/C recombinant were identified among selected prevalent infections. These results indicate that incident and prevalent HIV-1 infections in Rayong and Chon Buri during 1998-2001 were 90% CRF01_AE, 3% subtype B, and 7% either recombinant or dual. This study frames the genetic diversity of HIV-1 in these cohorts in their preparatory phase for the ongoing ALVACHIV (vCP1521) prime, AIDSVAX B/E boost, phase III vaccine trial and will provide a benchmark for interpretation and analysis." @default.
- W2078472336 created "2016-06-24" @default.
- W2078472336 creator A5001063157 @default.
- W2078472336 creator A5005840020 @default.
- W2078472336 creator A5019096476 @default.
- W2078472336 creator A5034787615 @default.
- W2078472336 creator A5038157410 @default.
- W2078472336 creator A5046715664 @default.
- W2078472336 creator A5046993544 @default.
- W2078472336 creator A5056904109 @default.
- W2078472336 creator A5072696926 @default.
- W2078472336 creator A5076820552 @default.
- W2078472336 creator A5083372870 @default.
- W2078472336 creator A5084387492 @default.
- W2078472336 creator A5087034401 @default.
- W2078472336 creator A5089352687 @default.
- W2078472336 creator A5091031676 @default.
- W2078472336 date "2006-08-01" @default.
- W2078472336 modified "2023-09-26" @default.
- W2078472336 title "Molecular Epidemiology of HIV Type 1 in Preparation for a Phase III Prime-Boost Vaccine Trial in Thailand and a New Approach to HIV Type 1 Genotyping" @default.
- W2078472336 cites W1965014591 @default.
- W2078472336 cites W1971801394 @default.
- W2078472336 cites W1976279192 @default.
- W2078472336 cites W1981118535 @default.
- W2078472336 cites W1986714123 @default.
- W2078472336 cites W1988251736 @default.
- W2078472336 cites W1992471261 @default.
- W2078472336 cites W2006552334 @default.
- W2078472336 cites W2011004634 @default.
- W2078472336 cites W2019041261 @default.
- W2078472336 cites W2024496859 @default.
- W2078472336 cites W2029406702 @default.
- W2078472336 cites W2037171810 @default.
- W2078472336 cites W2041291923 @default.
- W2078472336 cites W2045385055 @default.
- W2078472336 cites W2045790346 @default.
- W2078472336 cites W2047684280 @default.
- W2078472336 cites W2052466195 @default.
- W2078472336 cites W2054239484 @default.
- W2078472336 cites W2057461554 @default.
- W2078472336 cites W2064772958 @default.
- W2078472336 cites W2114299472 @default.
- W2078472336 cites W2129104892 @default.
- W2078472336 cites W2133878267 @default.
- W2078472336 cites W2135322737 @default.
- W2078472336 cites W2143745136 @default.
- W2078472336 cites W2151741901 @default.
- W2078472336 cites W2172055214 @default.
- W2078472336 cites W2338666648 @default.
- W2078472336 cites W87809020 @default.
- W2078472336 doi "https://doi.org/10.1089/aid.2006.22.801" @default.
- W2078472336 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16910837" @default.
- W2078472336 hasPublicationYear "2006" @default.
- W2078472336 type Work @default.
- W2078472336 sameAs 2078472336 @default.
- W2078472336 citedByCount "19" @default.
- W2078472336 countsByYear W20784723362012 @default.
- W2078472336 countsByYear W20784723362013 @default.
- W2078472336 countsByYear W20784723362015 @default.
- W2078472336 countsByYear W20784723362020 @default.
- W2078472336 crossrefType "journal-article" @default.
- W2078472336 hasAuthorship W2078472336A5001063157 @default.
- W2078472336 hasAuthorship W2078472336A5005840020 @default.
- W2078472336 hasAuthorship W2078472336A5019096476 @default.
- W2078472336 hasAuthorship W2078472336A5034787615 @default.
- W2078472336 hasAuthorship W2078472336A5038157410 @default.
- W2078472336 hasAuthorship W2078472336A5046715664 @default.
- W2078472336 hasAuthorship W2078472336A5046993544 @default.
- W2078472336 hasAuthorship W2078472336A5056904109 @default.
- W2078472336 hasAuthorship W2078472336A5072696926 @default.
- W2078472336 hasAuthorship W2078472336A5076820552 @default.
- W2078472336 hasAuthorship W2078472336A5083372870 @default.
- W2078472336 hasAuthorship W2078472336A5084387492 @default.
- W2078472336 hasAuthorship W2078472336A5087034401 @default.
- W2078472336 hasAuthorship W2078472336A5089352687 @default.
- W2078472336 hasAuthorship W2078472336A5091031676 @default.
- W2078472336 hasConcept C104317684 @default.
- W2078472336 hasConcept C107130276 @default.
- W2078472336 hasConcept C126322002 @default.
- W2078472336 hasConcept C135763542 @default.
- W2078472336 hasConcept C159047783 @default.
- W2078472336 hasConcept C2778190748 @default.
- W2078472336 hasConcept C2779690655 @default.
- W2078472336 hasConcept C2780727368 @default.
- W2078472336 hasConcept C2781209916 @default.
- W2078472336 hasConcept C2908647359 @default.
- W2078472336 hasConcept C3013748606 @default.
- W2078472336 hasConcept C31467283 @default.
- W2078472336 hasConcept C54355233 @default.
- W2078472336 hasConcept C71924100 @default.
- W2078472336 hasConcept C86803240 @default.
- W2078472336 hasConcept C97669555 @default.
- W2078472336 hasConcept C99454951 @default.
- W2078472336 hasConceptScore W2078472336C104317684 @default.
- W2078472336 hasConceptScore W2078472336C107130276 @default.
- W2078472336 hasConceptScore W2078472336C126322002 @default.
- W2078472336 hasConceptScore W2078472336C135763542 @default.
- W2078472336 hasConceptScore W2078472336C159047783 @default.
- W2078472336 hasConceptScore W2078472336C2778190748 @default.
- W2078472336 hasConceptScore W2078472336C2779690655 @default.