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- W2078474866 abstract "There is a perception that up to 40% of aspirin users may be resistant to aspirin, and given the widespread use of this drug to reduce cardiovascular risk, could this mean that large numbers of patients are not protected from atherothrombotic complications? A recent search on Medline for ‘aspirin resistance’ yielded 894 publications, including 188 review articles underlining the scientific interest in this phenomenon. These publications estimate that between 5.5% and 60% (!) of patients may have a degree of so-called ‘aspirin resistance’ [ 1 Bhatt D.L. Aspirin resistance: more than just a laboratory curiosity. J Am Coll Cardiol. 2004; 43: 1127-1129 Abstract Full Text Full Text PDF PubMed Scopus (110) Google Scholar , 2 Hankey G.J. Eikelboom J.W. Aspirin resistance. BMJ. 2004; 328: 477-479 Crossref PubMed Google Scholar , 3 Campbell C.L. Steinhubl S.R. Variability in response to aspirin: do we understand the clinical relevance?. J Thromb Haemost. 2005; 3: 665-669 Crossref PubMed Scopus (66) Google Scholar ]. The amount of published literature bears no relationship to the existence of an entity, as inhabitants around Loch Ness (where a creature is supposed to live within) in Scotland will testify, but it does make good publicity. However, the bottom line still remains on whether ‘aspirin resistance’ really does exist and if so, is it important." @default.
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- W2078474866 date "2007-01-01" @default.
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- W2078474866 title "Aspirin resistance: What, why and when?" @default.
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- W2078474866 doi "https://doi.org/10.1016/j.thromres.2006.08.009" @default.
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