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- W2078475098 abstract "The effects of Asp1-beta-amide-Val5-angiotensin II (A II) and Asp1-Ile5-angiotensin I (A I) have been studied on the isolated continuously superfused cat tracheal muscle contracted by 5-hydroxytryptamine (5-HT). Both peptides have been shown to induce dose-dependent relaxation on this muscle. Similar effects have been obtained with synthetic bradykinin, prostaglandin E2 (PGE2), noradrenaline and histamine. The effects of bradykinin, A I and A II have been shown to be inhibited by aspirin but not by propranolol, metiamide, SC 19220 or a specific, competitive antagonist of A II. The relaxing effect of A I is not due to the conversion of decapeptide to octapeptide A II. The possible mechanism of the relaxing effects of A I and A II on the cat isolated tracheal muscle is discussed." @default.
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- W2078475098 date "1976-04-01" @default.
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- W2078475098 title "The effects of angiotensin I and angiotensin II on the isolated tracheal muscle of the cat" @default.
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- W2078475098 doi "https://doi.org/10.1111/j.2042-7158.1976.tb04157.x" @default.
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