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- W2078481875 endingPage "149" @default.
- W2078481875 startingPage "144" @default.
- W2078481875 abstract "Thymic stromal lymphopoietin (TSLP) is an interleukin 7-like cytokine produced mainly by epithelial cells. Many studies indicate that TSLP contributes to promote T helper (Th) 2 immune responses which are associated with the pathogenesis of allergic inflammatory diseases. Base on the cross-talk between Th2 inflammation and cancers, we will highlight the role of TSLP in the progression of cancers in this review. TSLP is involved in the increasing prevalence of Tregs in the cancer microenvironment. Besides, TSLP has an important role in promoting the growth of vascular endothelial cells and angiogenesis, which could further promote the development and progression of cervical cancer. It gives the evidence that TSLP could induce EMT to promote cancer metastasis. In addition, TSLP could be detected in some fibroblasts and may play a role in the pathogenesis of non-allergic diseases characterized by a type 2 immune response and organ fibrosis." @default.
- W2078481875 created "2016-06-24" @default.
- W2078481875 creator A5009105694 @default.
- W2078481875 creator A5010206164 @default.
- W2078481875 creator A5032522966 @default.
- W2078481875 creator A5054756337 @default.
- W2078481875 date "2015-06-01" @default.
- W2078481875 modified "2023-10-04" @default.
- W2078481875 title "Functions of thymic stromal lymphopoietin in non-allergic diseases" @default.
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