FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078485026> ?p ?o ?g. }

• W2078485026 endingPage "e4073" @default.
• W2078485026 startingPage "e4073" @default.
• W2078485026 abstract "Herpesvirus infection of placenta may be harmful in pregnancy leading to disorders in fetal growth, premature delivery, miscarriage, or major congenital abnormalities. Although a correlation between human herpesvirus 8 (HHV-8) infection and abortion or low birth weight in children has been suggested, and rare cases of in utero or perinatal HHV-8 transmission have been documented, no direct evidence of HHV-8 infection of placenta has yet been reported. The aim of this study was to evaluate the in vitro and in vivo susceptibility of placental cells to HHV-8 infection. Short-term infection assays were performed on placental chorionic villi isolated from term placentae. Qualitative and quantitative HHV-8 detection were performed by PCR and real-time PCR, and HHV-8 proteins were analyzed by immunohistochemistry. Term placenta samples from HHV-8-seropositive women were analyzed for the presence of HHV-8 DNA and antigens. In vitro infected histocultures showed increasing amounts of HHV-8 DNA in tissues and supernatants; cyto- and syncitiotrophoblasts, as well as endothelial cells, expressed latent and lytic viral antigens. Increased apoptotic phenomena were visualized by the terminal deoxynucleotidyl transferase-mediated deoxyuridine nick end-labeling method in infected histocultures. Ex vivo, HHV-8 DNA and a latent viral antigen were detected in placenta samples from HHV-8-seropositive women. These findings demonstrate that HHV-8, like other human herpesviruses, may infect placental cells in vitro and in vivo, thus providing evidence that this phenomenon might influence vertical transmission and pregnancy outcome in HHV-8-infected women." @default.
• W2078485026 created "2016-06-24" @default.
• W2078485026 creator A5001293265 @default.
• W2078485026 creator A5001391327 @default.
• W2078485026 creator A5004887214 @default.
• W2078485026 creator A5016870943 @default.
• W2078485026 creator A5028191178 @default.
• W2078485026 creator A5029628556 @default.
• W2078485026 creator A5029818562 @default.
• W2078485026 creator A5042481462 @default.
• W2078485026 creator A5043421046 @default.
• W2078485026 creator A5050268365 @default.
• W2078485026 creator A5063721175 @default.
• W2078485026 creator A5069021176 @default.
• W2078485026 creator A5087573541 @default.
• W2078485026 creator A5089204174 @default.
• W2078485026 date "2008-12-30" @default.
• W2078485026 modified "2023-10-14" @default.
• W2078485026 title "In Vitro and In Vivo Human Herpesvirus 8 Infection of Placenta" @default.
• W2078485026 cites W1964714012 @default.
• W2078485026 cites W1972354979 @default.
• W2078485026 cites W1979760924 @default.
• W2078485026 cites W1980714130 @default.
• W2078485026 cites W1986455044 @default.
• W2078485026 cites W1993736301 @default.
• W2078485026 cites W2007090977 @default.
• W2078485026 cites W2007639993 @default.
• W2078485026 cites W2024970873 @default.
• W2078485026 cites W2026463254 @default.
• W2078485026 cites W2026894999 @default.
• W2078485026 cites W2032438721 @default.
• W2078485026 cites W2039484700 @default.
• W2078485026 cites W2039840913 @default.
• W2078485026 cites W2056748255 @default.
• W2078485026 cites W2058828603 @default.
• W2078485026 cites W2069586360 @default.
• W2078485026 cites W2088243322 @default.
• W2078485026 cites W2090649998 @default.
• W2078485026 cites W2092511671 @default.
• W2078485026 cites W2096375806 @default.
• W2078485026 cites W2116647385 @default.
• W2078485026 cites W2118597759 @default.
• W2078485026 cites W2120246830 @default.
• W2078485026 cites W2120268889 @default.
• W2078485026 cites W2125782614 @default.
• W2078485026 cites W2136554055 @default.
• W2078485026 cites W2143326007 @default.
• W2078485026 cites W2150306998 @default.
• W2078485026 cites W2156041649 @default.
• W2078485026 cites W2162857316 @default.
• W2078485026 cites W2169448416 @default.
• W2078485026 doi "https://doi.org/10.1371/journal.pone.0004073" @default.
• W2078485026 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2603597" @default.
• W2078485026 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19115001" @default.
• W2078485026 hasPublicationYear "2008" @default.
• W2078485026 type Work @default.
• W2078485026 sameAs 2078485026 @default.
• W2078485026 citedByCount "25" @default.
• W2078485026 countsByYear W20784850262012 @default.
• W2078485026 countsByYear W20784850262013 @default.
• W2078485026 countsByYear W20784850262014 @default.
• W2078485026 countsByYear W20784850262015 @default.
• W2078485026 countsByYear W20784850262017 @default.
• W2078485026 countsByYear W20784850262018 @default.
• W2078485026 countsByYear W20784850262019 @default.
• W2078485026 countsByYear W20784850262020 @default.
• W2078485026 countsByYear W20784850262021 @default.
• W2078485026 countsByYear W20784850262022 @default.
• W2078485026 countsByYear W20784850262023 @default.
• W2078485026 crossrefType "journal-article" @default.
• W2078485026 hasAuthorship W2078485026A5001293265 @default.
• W2078485026 hasAuthorship W2078485026A5001391327 @default.
• W2078485026 hasAuthorship W2078485026A5004887214 @default.
• W2078485026 hasAuthorship W2078485026A5016870943 @default.
• W2078485026 hasAuthorship W2078485026A5028191178 @default.
• W2078485026 hasAuthorship W2078485026A5029628556 @default.
• W2078485026 hasAuthorship W2078485026A5029818562 @default.
• W2078485026 hasAuthorship W2078485026A5042481462 @default.
• W2078485026 hasAuthorship W2078485026A5043421046 @default.
• W2078485026 hasAuthorship W2078485026A5050268365 @default.
• W2078485026 hasAuthorship W2078485026A5063721175 @default.
• W2078485026 hasAuthorship W2078485026A5069021176 @default.
• W2078485026 hasAuthorship W2078485026A5087573541 @default.
• W2078485026 hasAuthorship W2078485026A5089204174 @default.
• W2078485026 hasBestOaLocation W20784850261 @default.
• W2078485026 hasConcept C147483822 @default.
• W2078485026 hasConcept C159047783 @default.
• W2078485026 hasConcept C16685009 @default.
• W2078485026 hasConcept C172680121 @default.
• W2078485026 hasConcept C203014093 @default.
• W2078485026 hasConcept C2776953305 @default.
• W2078485026 hasConcept C2779234561 @default.
• W2078485026 hasConcept C2781385326 @default.
• W2078485026 hasConcept C54355233 @default.
• W2078485026 hasConcept C71924100 @default.
• W2078485026 hasConcept C86803240 @default.
• W2078485026 hasConceptScore W2078485026C147483822 @default.
• W2078485026 hasConceptScore W2078485026C159047783 @default.

• next