Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078486577> ?p ?o ?g. }
- W2078486577 endingPage "11742" @default.
- W2078486577 startingPage "11734" @default.
- W2078486577 abstract "The development of adhesive as well as antiadhesive surfaces is essential in various biomaterial applications. In this study, we have used a multidisciplinary approach that combines biological and physicochemical methods to progress in our understanding of cell−surface interactions. Four model surfaces have been used to investigate fibronectin (Fn) adsorption and the subsequent morphology and adhesion of preosteoblasts. Such experimental conditions lead us to distinguish between anti- and proadhesive substrata. Our results indicate that Fn is not able to induce cell adhesion on antiadhesive materials. On adhesive substrata, Fn did not increase the number of adherent cells but favored their spreading. This work also examined Fn−surface interactions using ELISA immunoassays, fluorescent labeling of Fn, and force spectroscopy with Fn-modified tips. The results provided clear evidence of the advantages and limitations of each technique. All of the techniques confirmed the important adsorption of Fn on proadhesive surfaces for cells. By contrast, antiadhesive substrata for cells avoided Fn adsorption. Furthermore, ELISA experiments enabled us to verify the accessibility of cell binding sites to adsorbed Fn molecules." @default.
- W2078486577 created "2016-06-24" @default.
- W2078486577 creator A5017339213 @default.
- W2078486577 creator A5026181500 @default.
- W2078486577 creator A5026474779 @default.
- W2078486577 creator A5057724189 @default.
- W2078486577 creator A5064952517 @default.
- W2078486577 date "2008-09-25" @default.
- W2078486577 modified "2023-10-17" @default.
- W2078486577 title "Probing Fibronectin−Surface Interactions: A Multitechnique Approach" @default.
- W2078486577 cites W1488956834 @default.
- W2078486577 cites W1927705072 @default.
- W2078486577 cites W1966157186 @default.
- W2078486577 cites W1967598259 @default.
- W2078486577 cites W1969956160 @default.
- W2078486577 cites W1970986900 @default.
- W2078486577 cites W1978399979 @default.
- W2078486577 cites W1978853218 @default.
- W2078486577 cites W1980723108 @default.
- W2078486577 cites W1980912753 @default.
- W2078486577 cites W1986638085 @default.
- W2078486577 cites W1986655848 @default.
- W2078486577 cites W1992848813 @default.
- W2078486577 cites W1995740638 @default.
- W2078486577 cites W1996509172 @default.
- W2078486577 cites W1999183148 @default.
- W2078486577 cites W2002387722 @default.
- W2078486577 cites W2003612867 @default.
- W2078486577 cites W2004824285 @default.
- W2078486577 cites W2007684474 @default.
- W2078486577 cites W2009140388 @default.
- W2078486577 cites W2010320204 @default.
- W2078486577 cites W2011126645 @default.
- W2078486577 cites W2028174136 @default.
- W2078486577 cites W2030352151 @default.
- W2078486577 cites W2037619201 @default.
- W2078486577 cites W2041202929 @default.
- W2078486577 cites W2045165252 @default.
- W2078486577 cites W2046490515 @default.
- W2078486577 cites W2053719494 @default.
- W2078486577 cites W2055428093 @default.
- W2078486577 cites W2057757462 @default.
- W2078486577 cites W2063016356 @default.
- W2078486577 cites W2067100232 @default.
- W2078486577 cites W2068322110 @default.
- W2078486577 cites W2068382911 @default.
- W2078486577 cites W2069284563 @default.
- W2078486577 cites W2080239685 @default.
- W2078486577 cites W2081103497 @default.
- W2078486577 cites W2081954098 @default.
- W2078486577 cites W2084102425 @default.
- W2078486577 cites W2084339147 @default.
- W2078486577 cites W2098799101 @default.
- W2078486577 cites W2104608387 @default.
- W2078486577 cites W2111903386 @default.
- W2078486577 cites W2113408435 @default.
- W2078486577 cites W2115044953 @default.
- W2078486577 cites W2120327693 @default.
- W2078486577 cites W2122757379 @default.
- W2078486577 cites W2122840995 @default.
- W2078486577 cites W2142988817 @default.
- W2078486577 cites W2145004194 @default.
- W2078486577 cites W2149205831 @default.
- W2078486577 cites W2160346250 @default.
- W2078486577 cites W2164986477 @default.
- W2078486577 cites W3011891279 @default.
- W2078486577 cites W4312422059 @default.
- W2078486577 doi "https://doi.org/10.1021/la801727p" @default.
- W2078486577 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18816077" @default.
- W2078486577 hasPublicationYear "2008" @default.
- W2078486577 type Work @default.
- W2078486577 sameAs 2078486577 @default.
- W2078486577 citedByCount "18" @default.
- W2078486577 countsByYear W20784865772012 @default.
- W2078486577 countsByYear W20784865772013 @default.
- W2078486577 countsByYear W20784865772015 @default.
- W2078486577 countsByYear W20784865772017 @default.
- W2078486577 countsByYear W20784865772018 @default.
- W2078486577 countsByYear W20784865772022 @default.
- W2078486577 crossrefType "journal-article" @default.
- W2078486577 hasAuthorship W2078486577A5017339213 @default.
- W2078486577 hasAuthorship W2078486577A5026181500 @default.
- W2078486577 hasAuthorship W2078486577A5026474779 @default.
- W2078486577 hasAuthorship W2078486577A5057724189 @default.
- W2078486577 hasAuthorship W2078486577A5064952517 @default.
- W2078486577 hasConcept C102951782 @default.
- W2078486577 hasConcept C119473381 @default.
- W2078486577 hasConcept C121332964 @default.
- W2078486577 hasConcept C12554922 @default.
- W2078486577 hasConcept C147789679 @default.
- W2078486577 hasConcept C1491633281 @default.
- W2078486577 hasConcept C150394285 @default.
- W2078486577 hasConcept C169274487 @default.
- W2078486577 hasConcept C171250308 @default.
- W2078486577 hasConcept C178790620 @default.
- W2078486577 hasConcept C185592680 @default.
- W2078486577 hasConcept C192562407 @default.
- W2078486577 hasConcept C2778414984 @default.