FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078488975> ?p ?o ?g. }

• W2078488975 endingPage "1660" @default.
• W2078488975 startingPage "1654" @default.
• W2078488975 abstract "<h3>Background:</h3> The factors that influence liver fibrosis progression in patients co-infected with human immunodeficiency virus/hepatitis C virus (HIV/HCV) are not completely understood. It is not known if insulin resistance (IR), a condition that promotes liver fibrosis in HCV mono-infected individuals, is one of these factors. <h3>Objective:</h3> To evaluate the association between IR and liver stiffness (LS). <h3>Design:</h3> Multicentre cross-sectional study. <h3>Patients:</h3> 330 patients co-infected with HIV/HCV. <h3>Methods:</h3> LS was assessed by transient elastography, which has shown a high accuracy to predict significant fibrosis in patients co-infected with HIV/HCV. The outcome variable of the study was LS. Patients with LS⩾9 kPa were considered as having significant fibrosis. IR was calculated using the HOMA method. <h3>Results:</h3> LS was ⩾9 kPa in 150 (45%) patients. HOMA correlated with LS (Spearman’s rho correlation coefficient, 0.37; p<0.0001). The median (Q1–Q3) HOMA in patients with LS⩾9 kPa was 3.30 (2.17–5.16) while it was 2.09 (1.37–3.22) in patients with LS <9 kPa (p<0.0001). Ninety-six (39%) individuals with a HOMA <4 and 54 (63%) with a HOMA ⩾4 showed LS⩾9 kPa (p<0.0001). Analyses after excluding patients with cirrhosis yielded similar results. After multivariate analyses, age ⩾40 years (adjusted odds ratio (AOR), 1.85; 95% confidence interval (CI), 1.03 to 3.29; p = 0.03), CD4 cell count <200 cells/ml (AOR, 3.45; 95% CI, 1.67 to 7.11; p = 0.001), hepatitis B virus co-infection (AOR, 9.25; 95% CI, 2.42 to 35.31; p = 0.001), and HOMA ⩾4 (AOR, 5.33; 95% CI, 2.70 to 10.49; p<0.0001) were the independent predictors of LS⩾9 kPa. <h3>Conclusion:</h3> IR is associated with LS in patients co-infected with HIV/HCV." @default.
• W2078488975 created "2016-06-24" @default.
• W2078488975 creator A5006610363 @default.
• W2078488975 creator A5008499391 @default.
• W2078488975 creator A5013551077 @default.
• W2078488975 creator A5018095966 @default.
• W2078488975 creator A5029106780 @default.
• W2078488975 creator A5041759120 @default.
• W2078488975 creator A5042665217 @default.
• W2078488975 creator A5043319601 @default.
• W2078488975 creator A5044646814 @default.
• W2078488975 creator A5052644280 @default.
• W2078488975 creator A5055471574 @default.
• W2078488975 creator A5063919113 @default.
• W2078488975 creator A5069411460 @default.
• W2078488975 creator A5070949389 @default.
• W2078488975 creator A5090139316 @default.
• W2078488975 date "2009-07-21" @default.
• W2078488975 modified "2023-10-17" @default.
• W2078488975 title "Insulin resistance is associated with liver stiffness in HIV/HCV co-infected patients" @default.
• W2078488975 cites W1963876199 @default.
• W2078488975 cites W1965906008 @default.
• W2078488975 cites W1968943752 @default.
• W2078488975 cites W1969562548 @default.
• W2078488975 cites W1972702648 @default.
• W2078488975 cites W1973775519 @default.
• W2078488975 cites W1975004114 @default.
• W2078488975 cites W1980737728 @default.
• W2078488975 cites W1987060364 @default.
• W2078488975 cites W1988208946 @default.
• W2078488975 cites W1988986320 @default.
• W2078488975 cites W1992357919 @default.
• W2078488975 cites W1994302207 @default.
• W2078488975 cites W2008132884 @default.
• W2078488975 cites W2010331469 @default.
• W2078488975 cites W2010509924 @default.
• W2078488975 cites W2012693748 @default.
• W2078488975 cites W2018117132 @default.
• W2078488975 cites W2022622170 @default.
• W2078488975 cites W2027498662 @default.
• W2078488975 cites W2036590128 @default.
• W2078488975 cites W2037387987 @default.
• W2078488975 cites W2040351784 @default.
• W2078488975 cites W2046500414 @default.
• W2078488975 cites W2047082256 @default.
• W2078488975 cites W2051984446 @default.
• W2078488975 cites W2059137735 @default.
• W2078488975 cites W2064583974 @default.
• W2078488975 cites W2066502865 @default.
• W2078488975 cites W2067166426 @default.
• W2078488975 cites W2068839916 @default.
• W2078488975 cites W2073293272 @default.
• W2078488975 cites W2074424133 @default.
• W2078488975 cites W2079872150 @default.
• W2078488975 cites W2080468761 @default.
• W2078488975 cites W2081737935 @default.
• W2078488975 cites W2082842671 @default.
• W2078488975 cites W2085956313 @default.
• W2078488975 cites W2101684160 @default.
• W2078488975 cites W2103156933 @default.
• W2078488975 cites W2126662952 @default.
• W2078488975 cites W2127375111 @default.
• W2078488975 cites W2130453232 @default.
• W2078488975 cites W2160234571 @default.
• W2078488975 cites W2165837785 @default.
• W2078488975 cites W2166665720 @default.
• W2078488975 cites W2171580291 @default.
• W2078488975 cites W2413381424 @default.
• W2078488975 cites W2416722695 @default.
• W2078488975 doi "https://doi.org/10.1136/gut.2009.179085" @default.
• W2078488975 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19625279" @default.
• W2078488975 hasPublicationYear "2009" @default.
• W2078488975 type Work @default.
• W2078488975 sameAs 2078488975 @default.
• W2078488975 citedByCount "30" @default.
• W2078488975 countsByYear W20784889752012 @default.
• W2078488975 countsByYear W20784889752013 @default.
• W2078488975 countsByYear W20784889752014 @default.
• W2078488975 countsByYear W20784889752015 @default.
• W2078488975 countsByYear W20784889752016 @default.
• W2078488975 countsByYear W20784889752017 @default.
• W2078488975 countsByYear W20784889752018 @default.
• W2078488975 crossrefType "journal-article" @default.
• W2078488975 hasAuthorship W2078488975A5006610363 @default.
• W2078488975 hasAuthorship W2078488975A5008499391 @default.
• W2078488975 hasAuthorship W2078488975A5013551077 @default.
• W2078488975 hasAuthorship W2078488975A5018095966 @default.
• W2078488975 hasAuthorship W2078488975A5029106780 @default.
• W2078488975 hasAuthorship W2078488975A5041759120 @default.
• W2078488975 hasAuthorship W2078488975A5042665217 @default.
• W2078488975 hasAuthorship W2078488975A5043319601 @default.
• W2078488975 hasAuthorship W2078488975A5044646814 @default.
• W2078488975 hasAuthorship W2078488975A5052644280 @default.
• W2078488975 hasAuthorship W2078488975A5055471574 @default.
• W2078488975 hasAuthorship W2078488975A5063919113 @default.
• W2078488975 hasAuthorship W2078488975A5069411460 @default.
• W2078488975 hasAuthorship W2078488975A5070949389 @default.
• W2078488975 hasAuthorship W2078488975A5090139316 @default.

• next