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- W2078515025 abstract "Age-related changes in the contents of crosslinking amino acids, histidinoalanine, pyridinoline, desmosine and isodesmosine, in human aorta were studied. Only the content of histidinoalanine was found to increase markedly with age throughout adult life. Histidinoalanine-containing peptides were isolated after the digestion of aorta with elastase and collagenase. The peptides were found to be acidic. It is proposed that histidinoalanine is formed between acidic structural proteins and elastin and between acidic structural proteins and collagen, and this cross-linking may be responsible for the aging of human aorta." @default.
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- W2078515025 date "1982-12-01" @default.
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- W2078515025 title "Aging and cross-linking in human aorta" @default.
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- W2078515025 doi "https://doi.org/10.1016/0006-291x(82)91913-1" @default.
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