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- W2078521617 abstract "In a recent work we have set forth the fundamental features of a new method devised for the investigation of the “reserve functional capacity of the pancreas.” We have shown for the first time that the subcutaneous or intravenous injection of duodenal secretin causes a fall in the blood sugar. This occurs in either normal men or experimental animals and the hypoglycemia thus produced results from an activation of the secretion of the islands of Langerhans. The reserve capacity of the normal pancreas can be represented quantitatively as the equivalent of 450 units of insulin. The amount of insulin required for the utilization of a normal carbohydrate ration of 500 grams is approximately 250 units, assuming, that, in round numbers, each two grams of sugar requires one unit. According to the experimental results of Woodyatt. Sansum and Wilder, the glucose tolerance of the healthy individual is 0.80 to 0.90 (approximately 0.85 grams per kgm. per hour). Accordingly, the quantity of glucose theoretically utiliz..." @default.
- W2078521617 created "2016-06-24" @default.
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- W2078521617 date "1931-03-01" @default.
- W2078521617 modified "2023-09-27" @default.
- W2078521617 title "THE RESERVE INCRETORY CAPACITY OF THE PANCREAS" @default.
- W2078521617 doi "https://doi.org/10.1210/endo-15-2-107" @default.
- W2078521617 hasPublicationYear "1931" @default.
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