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- W2078532092 abstract "Exposure to either cold or warm stress increased the thermal nociceptive thresholds of the terrestrial snail, Cepaea nemoralis. The warm stress-induced 'analgesia' was blocked by the prototypic opiate antagonist, naloxone, and the delta-opiate antagonist, ICI 154,129, and was suppressed by a 24-h pretreatment with the irreversible opiate antagonist, beta-funaltrexamine (B-FNA). In contrast, cold stress-induced analgesia was unaffected by either naloxone, ICI 154,129 or B-FNA. These results indicate that this mollusc displays both opioid and non-opioid forms of stress-induced analgesia in a manner analogous to that reported for mammals. These findings suggest an early evolutionary development and phylogenetic continuity of opioid and non-opioid mediated stress responses to aversive environmental stimuli." @default.
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- W2078532092 date "1987-04-01" @default.
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- W2078532092 title "Evidence for opioid and non-opioid forms of stress-induced analgesia in the snail, Cepaea nemoralis" @default.
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- W2078532092 doi "https://doi.org/10.1016/s0006-8993(87)80029-x" @default.
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