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- W2078548696 abstract "Aspects of sleep stage evaluation and analysis of alpha and delta EEG frequencies in sleep were shown to be related to musculoskeletal pain and mood disturbance in patients with ‘fibrositis syndrome’. Patients were treated at bedtime for 3 weeks with either chlorpromazine, 100 mg (8 patients), or l-tryptophan, 5 g (7 patienys). Chlorpromazine, but not l-tryptophan, was associated with increased slow wave sleep and amelioration of pain and mood symptoms. Mean percent time/min or mean percent power/min of alpha frequency during NREM and REM sleep correlated with overnight increase in pain measures, hostility, and decrease in energy. On the other hand, mean percent time/min of delta in NREM sleep was related to overnight decrease in pain and mean percent delta power/min was associated with decreased anxiety and hostility, and increased energy. Les aspects d'évaluation des stades de sommeil et d'analyse de fréquences EEG alpha et delta au cours du sommeil se sont révélés être liés à la douleur musculo-squelettique et aux perturbations de l'humeur chez des malades atteints de ‘fibrositis syndrome’. Ces malades ont été traités pendant 3 semaines par la prise, au moment du coucher, soit de chlorpromazine, 100 mg (8 malades) soit de l-tryptophane, 5 g (7 malades). La chlorpromazine, mais pas le l-tryptophane, entraîne une augmentation du sommeil à ondes lentes et une amélioration de la douleur et des troubles de l'humeur. Le pourcentage moyen de temps/min (ou le pourcentage moyen de puissance/min) des fréquences alpha au cours du sommeil REM et non-REM est corrélé à l'augmentation sur toute la nuit des mesures de douleur, hostilité, diminution d'énergie. Par ailleurs, le pourcentage moyen de temps/min d'activité delta au cours du sommeil NREM est corrélé à une diminution sur toute la nuit de la douleur et le pourcentage moyen de puissance delta/min est corrélé à une diminution de l'anxiété et de l'hostilité et à une augmentation de l'énergie." @default.
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- W2078548696 title "The relationship of alpha and delta EEG frequencies to pain and mood in ‘fibrositis’ patients treated with chlorpromazine and l-tryptophan" @default.
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- W2078548696 doi "https://doi.org/10.1016/0013-4694(80)90324-7" @default.
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