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- W2078588873 abstract "Several tetraoxane and 4-aminoquinoline molecules were prepared in order to examine the influence of ribofuranose as a carrier molecule on the antimalarial activity of test compounds. The synthesized compounds showed pronounced antimalarial activity against Plasmodium falciparum chloroquine susceptible D6, chloroquine resistant W2 and multidrug-resistant TM91C235 (Thailand) strains. The aminoquinoline derivative 4 was more active against W2 and TM91C235 strains than the control compounds (CQ and MFQ)." @default.
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- W2078588873 date "2008-01-01" @default.
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- W2078588873 title "Ribofuranose as a carrier of tetraoxane and 4-aminoquinoline antimalarial pharmacophores" @default.
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- W2078588873 doi "https://doi.org/10.2298/jsc0811021o" @default.
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