FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078595898> ?p ?o ?g. }

• W2078595898 endingPage "1029" @default.
• W2078595898 startingPage "1018" @default.
• W2078595898 abstract "To conduct a systematic review of the current evidence for the effects of stem cells on tendon healing in preclinical studies and human studies.A systematic search of the PubMed, CINAHL (Cumulative Index to Nursing and Allied Health Literature), Cochrane, and Embase databases was performed for stem cells and tendons with their associated terminology. Data validity was assessed, and data were collected on the outcomes of trials.A total of 27 preclinical studies and 5 clinical studies met the inclusion criteria. Preclinical studies have shown that stem cells are able to survive and differentiate into tendon cells when placed into a new tendon environment, leading to regeneration and biomechanical benefit to the tendon. Studies have been reported showing that stem cell therapy can be enhanced by molecular signaling adjunct, mechanical stimulation of cells, and the use of augmentation delivery devices. Studies have also shown alternatives to the standard method of bone marrow-derived mesenchymal stem cell therapy. Of the 5 human studies, only 1 was a randomized controlled trial, which showed that skin-derived tendon cells had a greater clinical benefit than autologous plasma. One cohort study showed the benefit of stem cells in rotator cuff tears and another in lateral epicondylitis. Two of the human studies showed how stem cells were successfully extracted from the humerus and, when tagged with insulin, became tendon cells.The current evidence shows that stem cells can have a positive effect on tendon healing. This is most likely because stem cells have regeneration potential, producing tissue that is similar to the preinjury state, but the results can be variable. The use of adjuncts such as molecular signaling, mechanical stimulation, and augmentation devices can potentially enhance stem cell therapy. Initial clinical trials are promising, with adjuncts for stem cell therapy in development." @default.
• W2078595898 created "2016-06-24" @default.
• W2078595898 creator A5006410845 @default.
• W2078595898 creator A5008262229 @default.
• W2078595898 creator A5009047702 @default.
• W2078595898 creator A5010107152 @default.
• W2078595898 creator A5023398449 @default.
• W2078595898 creator A5042446725 @default.
• W2078595898 date "2012-07-01" @default.
• W2078595898 modified "2023-10-16" @default.
• W2078595898 title "Exploring the Application of Stem Cells in Tendon Repair and Regeneration" @default.
• W2078595898 cites W1486827600 @default.
• W2078595898 cites W161184036 @default.
• W2078595898 cites W1913280318 @default.
• W2078595898 cites W1966148180 @default.
• W2078595898 cites W1974106192 @default.
• W2078595898 cites W1974756267 @default.
• W2078595898 cites W1980151308 @default.
• W2078595898 cites W1985479107 @default.
• W2078595898 cites W1986300999 @default.
• W2078595898 cites W1991977814 @default.
• W2078595898 cites W1993314665 @default.
• W2078595898 cites W1993682782 @default.
• W2078595898 cites W1997068847 @default.
• W2078595898 cites W2001467937 @default.
• W2078595898 cites W2007191221 @default.
• W2078595898 cites W2011935103 @default.
• W2078595898 cites W2012222854 @default.
• W2078595898 cites W2013057349 @default.
• W2078595898 cites W2019085298 @default.
• W2078595898 cites W2021903089 @default.
• W2078595898 cites W2023136127 @default.
• W2078595898 cites W2028103767 @default.
• W2078595898 cites W2029289084 @default.
• W2078595898 cites W2031820029 @default.
• W2078595898 cites W2035750370 @default.
• W2078595898 cites W2039665103 @default.
• W2078595898 cites W2041612304 @default.
• W2078595898 cites W2044712123 @default.
• W2078595898 cites W2046656259 @default.
• W2078595898 cites W2049086715 @default.
• W2078595898 cites W2052744783 @default.
• W2078595898 cites W2052800047 @default.
• W2078595898 cites W2054582866 @default.
• W2078595898 cites W2055235048 @default.
• W2078595898 cites W2057400150 @default.
• W2078595898 cites W2064279049 @default.
• W2078595898 cites W2077182018 @default.
• W2078595898 cites W2077723969 @default.
• W2078595898 cites W2085272535 @default.
• W2078595898 cites W2087136724 @default.
• W2078595898 cites W2092504238 @default.
• W2078595898 cites W2104460519 @default.
• W2078595898 cites W2105668403 @default.
• W2078595898 cites W2109861804 @default.
• W2078595898 cites W2116223288 @default.
• W2078595898 cites W2123177257 @default.
• W2078595898 cites W2127903102 @default.
• W2078595898 cites W2132594520 @default.
• W2078595898 cites W2136610282 @default.
• W2078595898 cites W2143419531 @default.
• W2078595898 cites W2150715279 @default.
• W2078595898 cites W2157780564 @default.
• W2078595898 cites W2158194225 @default.
• W2078595898 cites W2158837806 @default.
• W2078595898 cites W4249937174 @default.
• W2078595898 doi "https://doi.org/10.1016/j.arthro.2011.12.009" @default.
• W2078595898 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22381688" @default.
• W2078595898 hasPublicationYear "2012" @default.
• W2078595898 type Work @default.
• W2078595898 sameAs 2078595898 @default.
• W2078595898 citedByCount "92" @default.
• W2078595898 countsByYear W20785958982012 @default.
• W2078595898 countsByYear W20785958982013 @default.
• W2078595898 countsByYear W20785958982014 @default.
• W2078595898 countsByYear W20785958982015 @default.
• W2078595898 countsByYear W20785958982016 @default.
• W2078595898 countsByYear W20785958982017 @default.
• W2078595898 countsByYear W20785958982018 @default.
• W2078595898 countsByYear W20785958982019 @default.
• W2078595898 countsByYear W20785958982020 @default.
• W2078595898 countsByYear W20785958982021 @default.
• W2078595898 countsByYear W20785958982022 @default.
• W2078595898 countsByYear W20785958982023 @default.
• W2078595898 crossrefType "journal-article" @default.
• W2078595898 hasAuthorship W2078595898A5006410845 @default.
• W2078595898 hasAuthorship W2078595898A5008262229 @default.
• W2078595898 hasAuthorship W2078595898A5009047702 @default.
• W2078595898 hasAuthorship W2078595898A5010107152 @default.
• W2078595898 hasAuthorship W2078595898A5023398449 @default.
• W2078595898 hasAuthorship W2078595898A5042446725 @default.
• W2078595898 hasConcept C141071460 @default.
• W2078595898 hasConcept C142724271 @default.
• W2078595898 hasConcept C171056886 @default.
• W2078595898 hasConcept C198826908 @default.
• W2078595898 hasConcept C2776511800 @default.
• W2078595898 hasConcept C2779389132 @default.
• W2078595898 hasConcept C2780105995 @default.

• next