Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078597877> ?p ?o ?g. }
- W2078597877 endingPage "680" @default.
- W2078597877 startingPage "674" @default.
- W2078597877 abstract "The aim of the present study was to assess long-term survival of cadaveric second kidney allografts performed in our center and to determine risk factors predictive of long-term graft outcome.Of 1704 kidney transplantations performed between January 1985 and March 1998, 233 were second grafts. The majority of the recipients were sensitized. All patients were treated with the same quadruple immunosuppressive regimen.Kaplan-Meier analysis documented graft survival of 89% at 1 year, 76% at 5 years, and 53% at 10 years. Graft survival was similar for second and primary kidney transplants performed during the same period of time. When long-term second graft survival was examined, only two risk factors were found to be significant: (1) the degree of human leukocyte antigen (HLA) DR mismatch (MM) and (2) the number of acute rejection episodes. Multivariate analysis of several pre- and posttransplant variables also confirmed the importance of HLA MM (DR> A), but also, identified serum creatinine at 12 months as the most significant predictor of graft survival. In addition, the Cox proportional hazards model revealed that only the year of transplantation had an independent significant effect on acute rejection occurrence (RR = 0.591, 95%CI 0.437 to 0.801, P < 0.0007). Indeed, the incidence of acute rejection was found to decrease over time (44% of patients experienced at least one episode of acute rejection before 1990 vs. 17% after 1990).Finally, second graft long-term outcome shows an improved evolution according to the time period resulting from a strong decrease in acute rejection incidence and the impact of creatinine at 12 months." @default.
- W2078597877 created "2016-06-24" @default.
- W2078597877 creator A5000832841 @default.
- W2078597877 creator A5005455170 @default.
- W2078597877 creator A5009831609 @default.
- W2078597877 creator A5017334698 @default.
- W2078597877 creator A5023520056 @default.
- W2078597877 creator A5040930081 @default.
- W2078597877 creator A5043007943 @default.
- W2078597877 creator A5065766935 @default.
- W2078597877 creator A5069335681 @default.
- W2078597877 creator A5073392520 @default.
- W2078597877 creator A5084637045 @default.
- W2078597877 date "2003-08-01" @default.
- W2078597877 modified "2023-10-14" @default.
- W2078597877 title "Ten-year survival of second kidney transplants: Impact of immunologic factors and renal function at 12months" @default.
- W2078597877 cites W1964461041 @default.
- W2078597877 cites W1972481748 @default.
- W2078597877 cites W1982830254 @default.
- W2078597877 cites W1984857838 @default.
- W2078597877 cites W1993606933 @default.
- W2078597877 cites W1996741735 @default.
- W2078597877 cites W1998995166 @default.
- W2078597877 cites W2001317745 @default.
- W2078597877 cites W2001571617 @default.
- W2078597877 cites W2005942825 @default.
- W2078597877 cites W2008791529 @default.
- W2078597877 cites W2016096551 @default.
- W2078597877 cites W2021790643 @default.
- W2078597877 cites W2023893380 @default.
- W2078597877 cites W2030645483 @default.
- W2078597877 cites W2038713426 @default.
- W2078597877 cites W2040492897 @default.
- W2078597877 cites W2047843795 @default.
- W2078597877 cites W2050421097 @default.
- W2078597877 cites W2082373706 @default.
- W2078597877 cites W2085165414 @default.
- W2078597877 cites W2093399787 @default.
- W2078597877 cites W2093603781 @default.
- W2078597877 cites W2100422482 @default.
- W2078597877 cites W2143375046 @default.
- W2078597877 cites W2169639894 @default.
- W2078597877 cites W2333378480 @default.
- W2078597877 doi "https://doi.org/10.1046/j.1523-1755.2003.00104.x" @default.
- W2078597877 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12846765" @default.
- W2078597877 hasPublicationYear "2003" @default.
- W2078597877 type Work @default.
- W2078597877 sameAs 2078597877 @default.
- W2078597877 citedByCount "88" @default.
- W2078597877 countsByYear W20785978772012 @default.
- W2078597877 countsByYear W20785978772013 @default.
- W2078597877 countsByYear W20785978772014 @default.
- W2078597877 countsByYear W20785978772015 @default.
- W2078597877 countsByYear W20785978772016 @default.
- W2078597877 countsByYear W20785978772017 @default.
- W2078597877 countsByYear W20785978772018 @default.
- W2078597877 countsByYear W20785978772019 @default.
- W2078597877 countsByYear W20785978772020 @default.
- W2078597877 countsByYear W20785978772021 @default.
- W2078597877 countsByYear W20785978772022 @default.
- W2078597877 countsByYear W20785978772023 @default.
- W2078597877 crossrefType "journal-article" @default.
- W2078597877 hasAuthorship W2078597877A5000832841 @default.
- W2078597877 hasAuthorship W2078597877A5005455170 @default.
- W2078597877 hasAuthorship W2078597877A5009831609 @default.
- W2078597877 hasAuthorship W2078597877A5017334698 @default.
- W2078597877 hasAuthorship W2078597877A5023520056 @default.
- W2078597877 hasAuthorship W2078597877A5040930081 @default.
- W2078597877 hasAuthorship W2078597877A5043007943 @default.
- W2078597877 hasAuthorship W2078597877A5065766935 @default.
- W2078597877 hasAuthorship W2078597877A5069335681 @default.
- W2078597877 hasAuthorship W2078597877A5073392520 @default.
- W2078597877 hasAuthorship W2078597877A5084637045 @default.
- W2078597877 hasBestOaLocation W20785978771 @default.
- W2078597877 hasConcept C10515644 @default.
- W2078597877 hasConcept C120665830 @default.
- W2078597877 hasConcept C121332964 @default.
- W2078597877 hasConcept C126322002 @default.
- W2078597877 hasConcept C126894567 @default.
- W2078597877 hasConcept C141071460 @default.
- W2078597877 hasConcept C147483822 @default.
- W2078597877 hasConcept C159641895 @default.
- W2078597877 hasConcept C188280979 @default.
- W2078597877 hasConcept C203014093 @default.
- W2078597877 hasConcept C2780091579 @default.
- W2078597877 hasConcept C2780303639 @default.
- W2078597877 hasConcept C2780306776 @default.
- W2078597877 hasConcept C2781413609 @default.
- W2078597877 hasConcept C2911091166 @default.
- W2078597877 hasConcept C50382708 @default.
- W2078597877 hasConcept C61511704 @default.
- W2078597877 hasConcept C64518967 @default.
- W2078597877 hasConcept C71924100 @default.
- W2078597877 hasConcept C90924648 @default.
- W2078597877 hasConceptScore W2078597877C10515644 @default.
- W2078597877 hasConceptScore W2078597877C120665830 @default.
- W2078597877 hasConceptScore W2078597877C121332964 @default.
- W2078597877 hasConceptScore W2078597877C126322002 @default.