FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078605720> ?p ?o ?g. }

• W2078605720 endingPage "60" @default.
• W2078605720 startingPage "55" @default.
• W2078605720 abstract "Background Frontal fibrosing alopecia is a variety of cicatricial alopecia characterized by a band of frontal/frontoparietal hair recession and marked decrease or a complete loss of the eyebrows, typically observed in women who are postmenopausal. Objective The purpose of this study was to report clinical and histopathologic findings and results of treatment in a group of women affected by the disease. Method A total of 14 women with alopecia of the frontal hairline were evaluated from June 2000 through July 2003 in our outpatient consultation for hair disorders. Results Clinical examination revealed a band of symmetric recession of the frontoparietal hairline extending to the preauricular areas associated with loss of follicular orifices, mild skin atrophy, and perifollicular erythema at the scalp margin. In all, 9 patients also had partial or total loss of the eyebrows. The histologic features of the scalp specimens were similar in all our patients with a reduction of the number of hair follicles, and a high number of intermediate and velluslike follicles. Intemediate and velluslike follicles were more commonly affected than terminal follicles by the lymphocytic inflammatory infiltrate and perifollicular fibrosis. Conclusion Frontal fibrosing alopecia is a cicatricial alopecia that follows destruction of hair follicles by an inflammatory lymphocytic infiltrate that is localized around the upper portion of the hair follicle. It differs from lichen planopilaris because the lymphocytic infiltrate and fibrosis affect selectively the intermediate and the velluslike follicles of the frontal margin and eyebrows. The reason for this selective involvement is still unknown. Frontal fibrosing alopecia may represent a variety of lichen planopilaris with selective involvement of certain androgen-dependent areas. The affected follicles may have typical biologic markers that could explain the clinical and histologic features found in the disease. It is interesting to note that some of the patients treated with finasteride (2.5 mg/d) showed an arrest in the progression of the disease. Even if there is no proof for a hormonal basis of the disease, the effectiveness of finasteride in some patients may indicate that androgens might be partially responsible of the pathogenesis of the disease. Frontal fibrosing alopecia is a variety of cicatricial alopecia characterized by a band of frontal/frontoparietal hair recession and marked decrease or a complete loss of the eyebrows, typically observed in women who are postmenopausal. The purpose of this study was to report clinical and histopathologic findings and results of treatment in a group of women affected by the disease. A total of 14 women with alopecia of the frontal hairline were evaluated from June 2000 through July 2003 in our outpatient consultation for hair disorders. Clinical examination revealed a band of symmetric recession of the frontoparietal hairline extending to the preauricular areas associated with loss of follicular orifices, mild skin atrophy, and perifollicular erythema at the scalp margin. In all, 9 patients also had partial or total loss of the eyebrows. The histologic features of the scalp specimens were similar in all our patients with a reduction of the number of hair follicles, and a high number of intermediate and velluslike follicles. Intemediate and velluslike follicles were more commonly affected than terminal follicles by the lymphocytic inflammatory infiltrate and perifollicular fibrosis. Frontal fibrosing alopecia is a cicatricial alopecia that follows destruction of hair follicles by an inflammatory lymphocytic infiltrate that is localized around the upper portion of the hair follicle. It differs from lichen planopilaris because the lymphocytic infiltrate and fibrosis affect selectively the intermediate and the velluslike follicles of the frontal margin and eyebrows. The reason for this selective involvement is still unknown. Frontal fibrosing alopecia may represent a variety of lichen planopilaris with selective involvement of certain androgen-dependent areas. The affected follicles may have typical biologic markers that could explain the clinical and histologic features found in the disease. It is interesting to note that some of the patients treated with finasteride (2.5 mg/d) showed an arrest in the progression of the disease. Even if there is no proof for a hormonal basis of the disease, the effectiveness of finasteride in some patients may indicate that androgens might be partially responsible of the pathogenesis of the disease." @default.
• W2078605720 created "2016-06-24" @default.
• W2078605720 creator A5018285603 @default.
• W2078605720 creator A5022246846 @default.
• W2078605720 creator A5083993824 @default.
• W2078605720 creator A5084157436 @default.
• W2078605720 date "2005-01-01" @default.
• W2078605720 modified "2023-10-15" @default.
• W2078605720 title "Frontal fibrosing alopecia in postmenopausal women" @default.
• W2078605720 cites W1966214775 @default.
• W2078605720 cites W1977941371 @default.
• W2078605720 cites W1978420353 @default.
• W2078605720 cites W1992346109 @default.
• W2078605720 cites W1996062247 @default.
• W2078605720 cites W2011796309 @default.
• W2078605720 cites W2022418996 @default.
• W2078605720 cites W2040774516 @default.
• W2078605720 cites W2064614905 @default.
• W2078605720 cites W2082866145 @default.
• W2078605720 cites W2084402471 @default.
• W2078605720 cites W2162739295 @default.
• W2078605720 cites W4247322182 @default.
• W2078605720 doi "https://doi.org/10.1016/j.jaad.2004.05.014" @default.
• W2078605720 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15627081" @default.
• W2078605720 hasPublicationYear "2005" @default.
• W2078605720 type Work @default.
• W2078605720 sameAs 2078605720 @default.
• W2078605720 citedByCount "178" @default.
• W2078605720 countsByYear W20786057202012 @default.
• W2078605720 countsByYear W20786057202013 @default.
• W2078605720 countsByYear W20786057202014 @default.
• W2078605720 countsByYear W20786057202015 @default.
• W2078605720 countsByYear W20786057202016 @default.
• W2078605720 countsByYear W20786057202017 @default.
• W2078605720 countsByYear W20786057202018 @default.
• W2078605720 countsByYear W20786057202019 @default.
• W2078605720 countsByYear W20786057202020 @default.
• W2078605720 countsByYear W20786057202021 @default.
• W2078605720 countsByYear W20786057202022 @default.
• W2078605720 countsByYear W20786057202023 @default.
• W2078605720 crossrefType "journal-article" @default.
• W2078605720 hasAuthorship W2078605720A5018285603 @default.
• W2078605720 hasAuthorship W2078605720A5022246846 @default.
• W2078605720 hasAuthorship W2078605720A5083993824 @default.
• W2078605720 hasAuthorship W2078605720A5084157436 @default.
• W2078605720 hasConcept C126322002 @default.
• W2078605720 hasConcept C142724271 @default.
• W2078605720 hasConcept C156300145 @default.
• W2078605720 hasConcept C16005928 @default.
• W2078605720 hasConcept C2776360568 @default.
• W2078605720 hasConcept C2777216303 @default.
• W2078605720 hasConcept C2777524370 @default.
• W2078605720 hasConcept C2778515351 @default.
• W2078605720 hasConcept C2779121184 @default.
• W2078605720 hasConcept C2780559512 @default.
• W2078605720 hasConcept C2781172350 @default.
• W2078605720 hasConcept C2909877630 @default.
• W2078605720 hasConcept C71924100 @default.
• W2078605720 hasConceptScore W2078605720C126322002 @default.
• W2078605720 hasConceptScore W2078605720C142724271 @default.
• W2078605720 hasConceptScore W2078605720C156300145 @default.
• W2078605720 hasConceptScore W2078605720C16005928 @default.
• W2078605720 hasConceptScore W2078605720C2776360568 @default.
• W2078605720 hasConceptScore W2078605720C2777216303 @default.
• W2078605720 hasConceptScore W2078605720C2777524370 @default.
• W2078605720 hasConceptScore W2078605720C2778515351 @default.
• W2078605720 hasConceptScore W2078605720C2779121184 @default.
• W2078605720 hasConceptScore W2078605720C2780559512 @default.
• W2078605720 hasConceptScore W2078605720C2781172350 @default.
• W2078605720 hasConceptScore W2078605720C2909877630 @default.
• W2078605720 hasConceptScore W2078605720C71924100 @default.
• W2078605720 hasIssue "1" @default.
• W2078605720 hasLocation W20786057201 @default.
• W2078605720 hasLocation W20786057202 @default.
• W2078605720 hasOpenAccess W2078605720 @default.
• W2078605720 hasPrimaryLocation W20786057201 @default.
• W2078605720 hasRelatedWork W2004238377 @default.
• W2078605720 hasRelatedWork W2090996462 @default.
• W2078605720 hasRelatedWork W2156416389 @default.
• W2078605720 hasRelatedWork W2892480054 @default.
• W2078605720 hasRelatedWork W2894819756 @default.
• W2078605720 hasRelatedWork W3157765335 @default.
• W2078605720 hasRelatedWork W4249888343 @default.
• W2078605720 hasRelatedWork W2185528582 @default.
• W2078605720 hasRelatedWork W2586525536 @default.
• W2078605720 hasRelatedWork W3107153527 @default.
• W2078605720 hasVolume "52" @default.
• W2078605720 isParatext "false" @default.
• W2078605720 isRetracted "false" @default.
• W2078605720 magId "2078605720" @default.
• W2078605720 workType "article" @default.