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- W2078607898 abstract "ABSTRACT Myelodysplasia in Pediatric Patients. Evaluation of Current Classifications Introduction: Myelodysplastic Syndrome (MDS) in pediatrics is a rare and difficult clinical picture todiagnose. Classifications currently in use do not always help in identifying risk factors for leukemictransformation in children. Objective: To evaluate the value of current classifications by simultaneouslydetermining a) the frequency of MDS in a pediatric population b) applying CCC classification (category,cytopenias, cytogenetic) and Passmore score (risk score), and c) correlating with progression and evolutionto leukemia. Methods: Medical records of 56 children with cytopenias who were registered at the Hemato-oncology Unit, Hospital Roberto del Rio, were retrospectively reviewed from July 2000 to December 2007. Results: 13 patients met MDS diagnostic criteria (7.3% of the total hematological malignancies population).According to CCC classification, de novo MDS, refractory cytopenias with dysplasia and abnormalkaryotype were the most frequent features. All patients with a high Passmore score progressed toleukemia." @default.
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- W2078607898 date "2009-08-01" @default.
- W2078607898 modified "2023-09-24" @default.
- W2078607898 title "Mielodisplasia en Pacientes Pediátricos: Evaluación de Clasificaciones Actuales" @default.
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- W2078607898 doi "https://doi.org/10.4067/s0370-41062009000400005" @default.
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