FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078616320> ?p ?o ?g. }

• W2078616320 endingPage "221" @default.
• W2078616320 startingPage "214" @default.
• W2078616320 abstract "Purpose of review Measurements of whole-body energy expenditure, body composition, and in-vivo metabolic fluxes are required to quantitatively understand involuntary weight loss in cancer cachexia. Such studies are rare because cancer cachexia occurs near the end of life when invasive metabolic tests may be precluded. Thus, models of cancer-associated weight loss are an important tool for helping to understand this debilitating condition. Recent findings A computational model of human macronutrient metabolism was recently developed that simulates the normal metabolic adaptations to semi-starvation and re-feeding. Here, this model was used to integrate data on the metabolic changes in patients with cancer cachexia. The resulting computer simulations show how the known metabolic disturbances synergize with reduced energy intake to result in a progressive loss of body weight, fat mass, and fat-free mass. The model was also used to simulate the effects of nutritional support and investigate inhibition of lipolysis versus proteolysis as potential therapeutic approaches for cancer cachexia. Summary Computational modeling is a new tool that can integrate clinical data on the metabolic changes in cancer cachexia and provide a conceptual framework to help understand involuntary weight loss and predict the effects of potential therapies." @default.
• W2078616320 created "2016-06-24" @default.
• W2078616320 creator A5010704818 @default.
• W2078616320 creator A5045179101 @default.
• W2078616320 date "2008-05-01" @default.
• W2078616320 modified "2023-09-23" @default.
• W2078616320 title "Computational modeling of cancer cachexia" @default.
• W2078616320 cites W1967784390 @default.
• W2078616320 cites W1972732808 @default.
• W2078616320 cites W1977513872 @default.
• W2078616320 cites W1981215438 @default.
• W2078616320 cites W1985706453 @default.
• W2078616320 cites W1986173368 @default.
• W2078616320 cites W1996675676 @default.
• W2078616320 cites W2001885251 @default.
• W2078616320 cites W2004249948 @default.
• W2078616320 cites W2004773310 @default.
• W2078616320 cites W2008869575 @default.
• W2078616320 cites W2015843414 @default.
• W2078616320 cites W2022614975 @default.
• W2078616320 cites W2040509429 @default.
• W2078616320 cites W2043314733 @default.
• W2078616320 cites W2051968981 @default.
• W2078616320 cites W2068008235 @default.
• W2078616320 cites W2068258839 @default.
• W2078616320 cites W2068673501 @default.
• W2078616320 cites W2072187538 @default.
• W2078616320 cites W2075978435 @default.
• W2078616320 cites W2078608486 @default.
• W2078616320 cites W2080138425 @default.
• W2078616320 cites W2081578487 @default.
• W2078616320 cites W2106867120 @default.
• W2078616320 cites W2109956558 @default.
• W2078616320 cites W2113999158 @default.
• W2078616320 cites W2114467408 @default.
• W2078616320 cites W2120629110 @default.
• W2078616320 cites W2122535362 @default.
• W2078616320 cites W2127115822 @default.
• W2078616320 cites W2130377214 @default.
• W2078616320 cites W2165340329 @default.
• W2078616320 cites W2168854431 @default.
• W2078616320 cites W2320153740 @default.
• W2078616320 cites W2415271518 @default.
• W2078616320 cites W4205151726 @default.
• W2078616320 cites W4210957234 @default.
• W2078616320 cites W4247144442 @default.
• W2078616320 doi "https://doi.org/10.1097/mco.0b013e3282f9ae4d" @default.
• W2078616320 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2693333" @default.
• W2078616320 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18403915" @default.
• W2078616320 hasPublicationYear "2008" @default.
• W2078616320 type Work @default.
• W2078616320 sameAs 2078616320 @default.
• W2078616320 citedByCount "30" @default.
• W2078616320 countsByYear W20786163202013 @default.
• W2078616320 countsByYear W20786163202015 @default.
• W2078616320 countsByYear W20786163202016 @default.
• W2078616320 countsByYear W20786163202018 @default.
• W2078616320 countsByYear W20786163202019 @default.
• W2078616320 countsByYear W20786163202020 @default.
• W2078616320 countsByYear W20786163202021 @default.
• W2078616320 countsByYear W20786163202022 @default.
• W2078616320 crossrefType "journal-article" @default.
• W2078616320 hasAuthorship W2078616320A5010704818 @default.
• W2078616320 hasAuthorship W2078616320A5045179101 @default.
• W2078616320 hasBestOaLocation W20786163202 @default.
• W2078616320 hasConcept C121608353 @default.
• W2078616320 hasConcept C126322002 @default.
• W2078616320 hasConcept C134018914 @default.
• W2078616320 hasConcept C140985366 @default.
• W2078616320 hasConcept C171089720 @default.
• W2078616320 hasConcept C2777704314 @default.
• W2078616320 hasConcept C2986317502 @default.
• W2078616320 hasConcept C3020092424 @default.
• W2078616320 hasConcept C511355011 @default.
• W2078616320 hasConcept C544821477 @default.
• W2078616320 hasConcept C60644358 @default.
• W2078616320 hasConcept C71924100 @default.
• W2078616320 hasConcept C86803240 @default.
• W2078616320 hasConceptScore W2078616320C121608353 @default.
• W2078616320 hasConceptScore W2078616320C126322002 @default.
• W2078616320 hasConceptScore W2078616320C134018914 @default.
• W2078616320 hasConceptScore W2078616320C140985366 @default.
• W2078616320 hasConceptScore W2078616320C171089720 @default.
• W2078616320 hasConceptScore W2078616320C2777704314 @default.
• W2078616320 hasConceptScore W2078616320C2986317502 @default.
• W2078616320 hasConceptScore W2078616320C3020092424 @default.
• W2078616320 hasConceptScore W2078616320C511355011 @default.
• W2078616320 hasConceptScore W2078616320C544821477 @default.
• W2078616320 hasConceptScore W2078616320C60644358 @default.
• W2078616320 hasConceptScore W2078616320C71924100 @default.
• W2078616320 hasConceptScore W2078616320C86803240 @default.
• W2078616320 hasIssue "3" @default.
• W2078616320 hasLocation W20786163201 @default.
• W2078616320 hasLocation W20786163202 @default.
• W2078616320 hasLocation W20786163203 @default.
• W2078616320 hasLocation W20786163204 @default.
• W2078616320 hasOpenAccess W2078616320 @default.
• W2078616320 hasPrimaryLocation W20786163201 @default.

• next