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- W2078617070 abstract "A combination of nonresective and minimally resective (NRMR) procedures were used to treat a series of patients with intractable seizures who were poor candidates for conventional epilepsy surgery because of their independent bihemispheric seizure foci. Over the past 5 years, 10 patients with bihemispheric seizure foci have had seizure surgeries on both hemispheres and have had postoperative follow-up for a minimum of 6 months. Preoperative investigations included magnetic resonance (MR) imaging, positron emission tomography (PET) scanning, and video-EEG monitoring with surface and subdural electrodes. Multiple subpial cortical transection (MST) was the primary procedure in all 10 patients. Following MST, 8 patients had minimal cortical resection (topectomy) in areas that continued to show epileptiform discharges in prolonged trains on intraoperative corticography. In addition, stereotactic amygdalohippocampotomy was performed on 2 patients. The longest follow-up is 62 months, with a median of 16 months. Five patients are free of seizures; 3 have rare seizures; 1 has >90% reduction in seizure frequency; and 1 has complete cessation of myoclonic seizures with >50% reduction in frequency of complex partial seizures. There were no complications from any of the procedures. The results indicate that seizures originating from both hemispheres can be effectively and safely controlled by a combination of surgical procedures." @default.
- W2078617070 created "2016-06-24" @default.
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- W2078617070 date "1997-07-01" @default.
- W2078617070 modified "2023-09-27" @default.
- W2078617070 title "Surgical management of independent bihemispheric seizure foci" @default.
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- W2078617070 doi "https://doi.org/10.1016/s0896-6974(97)84200-4" @default.
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