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• W2078634485 abstract "Determination of sCD14-ST (presepsin) concentration as a marker for infections in newborns was not performed till now. 1. Assessment of blood presepsin concentration in newborns, including their sex, fetal maturity, birth weight, early-onset sepsis. 2. Determination of correlation between presepsin value and CRP, procalcitonin concentrations and some hematological parameters. The study comprised 45 newborns, among them 27 septic and 18 without infection, but with perinatal risk factors or symptoms suggesting infection, in which by rapid chemiluminescent enzyme immunoassay, using Pathfast TM analyser from Mitsubishi Kagaku Iatron, sCD14-ST concentration in whole blood was measured. The mean presepsin concentration in septic newborns (1772 ± 1009 pg/ml) was significantly higher than in group without infection (556 ± 158). Positive correlations between sCD14-ST and CRP, procalcitonin concentrations and negative correlations between the value of presepsin and Ht, Hb, platelet count, birth weight and fetal maturity were noted. 1. In newborns with early-onset sepsis, independently of their sex, birth weight, fetal maturity, significant increase presepsin concentration, correlating with increase of CRP and procalcitonin values and with decrease of platelet count, Hb and Ht. 2. Measurement of presepsin concentration in neonatal whole blood may be usefulness in diagnosis of early-onset sepsis." @default.
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• W2078634485 date "2013-09-01" @default.
• W2078634485 modified "2023-09-27" @default.
• W2078634485 title "Presepsyna (rozpuszczalny podtyp CD14-ST) jako diagnostyczny biomarker posocznicy u noworodków" @default.
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• W2078634485 doi "https://doi.org/10.1016/j.pepo.2013.06.011" @default.
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